1. Phase angle as a prognostic indicator of surgical outcomes in patients with gastrointestinal cancerJana Gulin, Ester Ipavic, Denis Mlakar-Mastnak, Erik Brecelj, Ibrahim Edhemović, Nada Rotovnik-Kozjek, 2023, original scientific article Keywords: phase angle, colorectal cancer, postoperative complications, malnutrition
Published in DiRROS: 26.07.2024; Views: 11; Downloads: 5
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2. Monitoring the effect of perioperative nutritional care on body composition and functional status in patients with carcinoma of gastrointestinal and hepatobiliary system and pancreasAndrej Gyergyek, Nada Rotovnik-Kozjek, Jasna Klen, 2023, original scientific article Abstract: Background. The significance of nutritional care in the management of cancer, particularly in the surgical treatment of abdominal cancer, is increasingly acknowledged. Body composition analysis, such as the Bioelectric impedance assay (BIA), and functional tests, e.g., handgrip strength, are used when assessing nutritional status alongside general and nutritional history, clinical examination, and laboratory tests. The primary approach in nutritional care is individually adjusted nutritional counselling and the use of medical nutrition, especially oral nutritional supplements. The aim of the study was to investigate the effects of perioperative nutritional care on body composition and functional status in patients with carcinoma of the gastrointestinal tract, hepatobiliary system, and pancreas. Patients and methods. 47 patients were included, 27 received preoperative and postoperative nutritional counselling and oral nutritional supplements (Group 1), while 20, due to surgical or organisational reasons, received nutritional care only postoperatively (Group 2). The effect of nutritional therapy was measured with bioimpedance body composition and handgrip measurements. Results. Group 2 had a higher average Nutritional Risk Screening (NRS) 2002 score upon enrolment (3 vs. 2 points); however, there was no difference when malnutrition was assessed using Global Leadership in Malnutrition (GLIM) criteria. There was a relative increase in lean body mass and fat-free mass index (FFMI) 7 days after surgery in group 1 (+4,2% vs. -2,1% in group 2). There was no difference in handgrip strength. Conclusions. Our results indicate that combined preoperative and postoperative nutritional care is superior to only postoperative nutritional care. It seems to prevent statistically significant lean mass loss 7 days after surgery but not after 14 days or 4 weeks.
Keywords: abdominal cancer, nutritional status, body composition
Published in DiRROS: 25.07.2024; Views: 20; Downloads: 3
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3. Mesenteric ischemia after capecitabine treatment in rectal cancer and resultant short bowel syndrome is not an absolute contraindication for radical oncological treatmentAna Perpar, Erik Brecelj, Nada Rotovnik-Kozjek, Franc Anderluh, Irena Oblak, Marija Skoblar Vidmar, Vaneja Velenik, 2015, other scientific articles Abstract: Thrombotic events, arterial or venous in origin, still remain a source of substantial morbidity and mortality in cancer patients. The propensity for their development in oncology patients is partially a consequence of the disease itself and partially a result of our attempts to treat it. One of the rarest and deadliest thromboembolic complications is arterial mesenteric ischemia. The high mortality rate is caused by its rarity and by its non-specific clinical presentation, both of which make early diagnosis and treatment difficult. Hence, most diagnoses and treatments occur late in the course of the disease. The issue survivors of arterial mesenteric ischemia may face is short bowel syndrome, which has become a chronic condition after the introduction of parenteral nutrition at home. We present a 73-year-old rectal cancer patient who developed acute arterial mesenteric thrombosis at the beginning of the pre-operative radiochemotherapy. Almost the entire length of his small intestine, except for the proximal 50 cm of it, and the ascending colon had to be resected. After multiorgan failure his condition improved, and he was able to successfully complete radical treatment (preoperative radiotherapy and surgery) for the rectal carcinoma, despite developing short bowel syndrome (SBS) and being dependent upon home-based parenteral nutrition to fully cover his nutritional needs. Mesenteric ischemia and resultant short bowel syndrome are not absolute contraindications for radical oncological treatment since such patients can still achieve long-term remission.
Keywords: acute mesenteric ischemia, capecitabine, multiorgan failure, rectal cancer, short bowel syndrome
Published in DiRROS: 23.04.2024; Views: 221; Downloads: 58
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5. Klinična prehrana onkološkega bolnika : ESPEN in ESMO smerniceKarla Berlec, Nada Rotovnik-Kozjek, 2022, published scientific conference contribution Abstract: Rakasta kaheksija je presnovna motnja, ki je povezana s slabšo kakovostjo življenja, slabšim odzivom na zdravljenje, številnejšimi zapleti med zdravljenjem in krajšim preživetjem. Rakasta bolezen je za človeško telo stres, ki mu sledi celoviti nevroendokrini in vnetni odziv. Spremeni se potreba po posameznih hranilih in uporaba hranil, presnovne spremembe so še dodatno poglobijo zaradi zdravljenja. Zato bolniki potrebujejo presnovnim potrebam prilagojeno prehrano. Ta se doseže z opredelitvijo njihovega prehranskega stanja. Prehransko stanje se lahko opredeli s prehranskim presejanjem ali natančnejšo oceno prehranskega stanja, katerega izvede ustrezno izobražen zdravnik, medicinska sestra ali klinični dietetik. S prehransko podporo onkoloških bolnikov preprečujemo podhranjenost bolnikov, katera močno pospeši kahektične procese, z njo poskušamo čim dlje ohranjati funkcionalno mišično maso ter s tem bolnikovo kondicijo in kvaliteto življenja. Prehranska podpora in terapije motenj prehranskega stanja predstavljajo del sodobne multidisciplinarne terapije onkoloških bolnikov, ki se izvaja po modelu vzporednih terapevtskih poti.
Keywords: onkološki bolniki, klinična prehrana, klinične smernice
Published in DiRROS: 16.01.2023; Views: 727; Downloads: 228
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6. Vloga prehranske obravnave pri zdravljenju bolnikov z rakom glave in vratuNada Rotovnik-Kozjek, 2022, published professional conference contribution Abstract: Prehranska ogroženost bolnikov z raki glave in vratu je zelo velika in pomeni resno oviro za optimalno zdravljenje teh bolnikov. Klinično stanje bolnikov pogosto opišemo kot sindromom glave in vratu. Ker je izguba telesne mase > 10 % značilno povezana s slabšim preživetjem bolnikov z rakom, sta prehranska podpora in terapija motenj prehranskega stanja integralni del zdravljenja bolnikov z rakom glave in vratu. V prispevku so prikazani rezultati pregleda literature, na osnovi katerih lahko sledimo strokovnim priporočilom klinične prehrane, ki jih individualno prilagajamo bolnikom in načinom zdravljenja. Prehranska obravnava bolnikov z rakom glave in vratu je paralelna terapevtska pot, ki je integrirana v proces zdravljenja rakave bolezni. Upoštevanje strokovnih priporočil klinične prehrane izboljša kakovost življenja bolnikov in učinkovitost zdravljenja rakov glave in vratu.
Keywords: rak glave in vratu, prehrana, onkološko zdravljenje
Published in DiRROS: 06.01.2023; Views: 491; Downloads: 143
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7. Smernice za zdravljenje bolnikov z rakom požiralnika in ezofagogastričnega stika (EGS)Franc Anderluh, Marko Boc, Goran Gačevski, Gorana Gašljević, Samo Horvat, Nežka Hribernik, Marija Ignjatović, Ana Jeromen, Jera Jeruc, Peter Korošec, Tanja Mesti, Srdjan Novaković, Irena Oblak, Janja Ocvirk, Martina Reberšek, Nada Rotovnik-Kozjek, Matevž Srpčič, Ajra Šečerov Ermenc, Borut Štabuc, Vaneja Velenik, Neva Volk, Vesna Zadnik, 2022, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: rak požiralnika, rak ezofagogastritičnega stika, smernice, zdravljenje
Published in DiRROS: 07.09.2022; Views: 934; Downloads: 341
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9. Priporočila za obravnavo bolnikov z rakom debelega črevesa in danke2020, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: rak debelega črevesa, rak danke, bolniki, zdravljenje
Published in DiRROS: 18.03.2022; Views: 1002; Downloads: 536
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10. Klinična pot celostne rehabilitacije bolnikov z rakom dojkeNikola Bešić, Simona Borštnar, Andreja Gornjec, Teja Kovačec Hermann, Vesna Homar, Denis Mlakar-Mastnak, Nataša Kos, Nada Rotovnik-Kozjek, Mateja Kurir-Borovčić, Tanja Marinko, Andreja Cirila Škufca Smrdel, Branka Stražišar, Tanja Španić, Lorna Zadravec-Zaletel, 2020, final research report Keywords: rak dojke, bolniki, zdravljenje, klinične poti
Published in DiRROS: 14.03.2022; Views: 917; Downloads: 449
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