1. Completely resected stage III melanoma controversy : 15 years of national tertiary centre experienceBarbara Perić, Sara Milićević, Andraž Perhavec, Marko Hočevar, Janez Žgajnar, 2021, original scientific article Abstract: Background Two prospective randomized studies analysing cutaneous melanoma (CM) patients with sentinel lymph node (SLN) metastases and rapid development of systemic adjuvant therapy have changed our approach to stage III CM treatment. The aim of this study was to compare results of retrospective survival analysis of stage III CM patients% treatment from Slovenian national CM register to leading international clinical guidelines. Patients and methods Since 2000, all Slovenian CM patients with primary tumour % TIb are treated at the Institute of Oncology Ljubljana and data are prospectively collected into a national CM registry. A retrospective analysis of 2426 sentinel lymph node (SLN) biopsies and 789 lymphadenectomies performed until 2015 was conducted using Kaplan-Meier survival curves and log-rank tests. Results Positive SLN was found in 519/2426 (21.4%) of patients and completion dissection (CLND) was performed in 455 patients. The 5-year overall survival (OS) of CLND group was 58% vs. 47% of metachronous metastases group (MLNM) (p = 0.003). The 5-year OS of patients with lymph node (LN) metastases and unknown primary site (UPM) was 45% vs. 21% of patients with synchronous LN metastasis. Patients with SLN tumour burden < 0.3 mm had 5-year OS similar to SLN negative patients (86% vs. 85%; p = 0.926). The 5-year OS of patients with burden > 1.0 mm was similar to the MLNM group (49% vs. 47%; p = 0.280). Conclusions Stage III melanoma patients is a heterogeneous group with significant OS differences. CLND after positive SLNB might still remain a method of treatment for selected patients with stage III.
Keywords: cutaneous melanoma, surgery treatment, sentinel node biopsy
Published in DiRROS: 17.07.2024; Views: 7; Downloads: 4
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2. Evaluating seagrass meadow dynamics by integrating field-based and remote sensing techniquesDanijel Ivajnšič, Martina Orlando-Bonaca, Daša Donša, Jaša Veno Grujić, Domen Trkov, Borut Mavrič, Lovrenc Lipej, 2022, original scientific article Abstract: Marine phanerogams are considered biological sentinels or indicators since any modification in seagrass meadow distribution and coverage signals negative changes in the marine environment. In recent decades, seagrass meadows have undergone global losses at accelerating rates, and almost one-third of their coverage has disappeared globally. This study focused on the dynamics of seagrass meadows in the northern Adriatic Sea, which is one of the most anthropogenically affected areas in the Mediterranean Sea. Seagrass distribution data and remote sensing products were utilized to identify the stable and dynamic parts of the seagrass ecosystem. Different seagrass species could not be distinguished with the Sentinel-2 (BOA) satellite image. However, results revealed a generally stable seagrass meadow (283.5 Ha) but, on the other hand, a stochastic behavior in seagrass meadow retraction (90.8 Ha) linked to local environmental processes associated with anthropogenic activities or climate change. If systemized, this proposed approach to monitoring seagrass meadow dynamics could be developed as a spatial decision support system for the entire Mediterranean basin. Such a tool could serve as a key element for decision makers in marine protected areas and would potentially support more effective conservation and management actions in these highly productive and important environments.
Keywords: Adriatic Sea, seagrass meadow, change analysis, Cimodocea nodosa, image classifiers, Sentinel-2, marine biology, hydrobiology
Published in DiRROS: 16.07.2024; Views: 15; Downloads: 4
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3. Modern treatment of vulvar cancerSebastjan Merlo, 2020, review article Abstract: Vulvar cancer accounts for 3%5% of malignant diseases of the female genital tract. The Slovenian incidence rate is 5.5/100,000, which means 57 new cases per year. The most common histological type (90%) is squamous cell carcinoma. Based on etiology, it can be classified into the first type which correlates with human papillomavirus (HPV) infection and the second type which is not associated with HPV. The most common and long-lasting symptom of vulvar cancer is pruritus. The preferred diagnostic procedure to confirm the diagnosis is a punch or incision biopsy. Surgery in combination with radiotherapy is the standard treatment for vulvar cancer. Sentinel lymph node biopsy with lymphoscintigraphy is now a standard part of surgical treatment. Chemotherapy is a palliative treatment option. Conclusions. Vulvar cancer is a rare disease. Because of the pathogenesis, surgery and radiotherapy are the main treatment modalities. The sentinel node biopsy (SNB) represents a contemporary approach to the vulvar cancer treatment and significantly reduces morbidity. Improvements in treatment of vulvar cancer contributed to the decrease of mortality among Slovenian women.
Keywords: vulvar cancer, surgical treatment, sentinel lymph node biopsy, lymphoscintigraphy
Published in DiRROS: 16.07.2024; Views: 13; Downloads: 3
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4. Towards the development of a landslide activity map in SloveniaMateja Jemec Auflič, Krištof Oštir, Tanja Grabrijan, Matjaž Ivačič, Tina Peternel, Ela Šegina, 2024, original scientific article Abstract: To create the landslide activity map, we implemented and tested the procedure to fully utilise the 6-day repeatability of the Sentinel-1 constellation in three pilot areas in Slovenia for the observation period from 2017 to 2021. The interferometric processing of the Sentinel-1 images was carried out with ENVI SARScape, while the interpretation of the persistent scatterers InSAR data was done in three steps. In the first step, a preliminary interpretation of the landslide areas was performed by integrating the PS InSAR data into a GIS environment with information that could be relevant to explain the movement patterns of the PS InSAR points. In the second step, a field validation was performed to check the PS InSAR in the field and record the potential damage to the objects indicating the slope mass movements. In the third step, the deformations were identified, and areas of significant movement were determined, consisting of clusters of at least 3 persistent scatterers (PS) with a maximum spacing of 10 m. The landslide activity map was created based on the landslide areas categorised into four classes based on the geotechnical analyses, yearly velocity data obtained by PS InSAR, and validation of annual velocity data obtained by in-situ and GNSS monitoring and field observation. A total of 21 polygons with different landslide activities were identified in three study areas. The overall methodology will help stakeholders in the early mapping and monitoring of landslides to increase the urban resilience.
Keywords: landslides, EO data, sentinel, time series, methodology, Slovenia
Published in DiRROS: 30.04.2024; Views: 256; Downloads: 180
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5. Land surface phenology from satellite data : technical reportUrška Kanjir, Ana Potočnik Buhvald, Mitja Skudnik, Liza Stančič, Krištof Oštir, 2022, treatise, preliminary study, study Keywords: phenology, forest, remote sensing, MODIS, Sentinel-2, vegetation indices
Published in DiRROS: 29.12.2022; Views: 564; Downloads: 169
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6. Razlike v fenološkem razvoju prevladujočih drevesnih vrst na Pahernikovi gozdni posesti ocenjene z analizo satelitskih posnetkovAnže Martin Pintar, David Hladnik, 2019, original scientific article Abstract: Fenološke razlike prevladujočih drevesnih vrst na območju Pahernikove posesti smo ocenjevali na podlagi satelitskih posnetkov misije Sentinel-2. Analizirali smo normirane diferencialne vegetacijske indekse (NDVI) v obdobju od 29. marca do 15. oktobra 2017. Na podlagi razlik v vegetacijskem indeksu NDVI je mogoče ocenjevati fenološki razvoj prevladujočih drevesnih vrst bukve (Fagus sylvatica L.), smreke (Picea abies L. (Karsten)) in macesna (Larix decidua Mill.) v gozdnih sestojih. Na območju posesti ugotavljamo omejitve ocenjevanja fenološkega razvoja smreke v mešanih sestojih smreke in jelke (Abies alba Mill.), ki imajo podobne vrednosti NDVI. Pri bukvi pa smo ugotovili manjšanje vrednosti NDVI na posnetkih 21. aprila in 5. oktobra z višanjem nadmorske višine, kar povezujemo s poznejšim olistanjem in hitrejšim rumenenjem listov bukve na višjih nadmorskih višinah.
Keywords: raznodobni gozdovi, bukev, Fagus sylvatica L., smreka, Picea abies L. (Karsten), gradient nadmorske višine, Sentinel-2, NDVI, kompozitna slika, Dravsko Pohorje
Published in DiRROS: 19.10.2019; Views: 3044; Downloads: 847
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7. Forewarned is forearmed : harmonized approaches for early detection of potentially invasive pests and pathogens in sentinel plantingsCarmen Morales-Rodríguez, Sten Anslan, Marie-Anne Auger-Rozenberg, Sylvie Augustin, Yuri Baranchikov, Amani Bellahirech, Daiva Burokiene, Dovile Čepukoit, Ejup Çota, Kateryna Davydenko, Maarten De Groot, 2019, original scientific article Abstract: The number of invasive alien pest and pathogen species affecting ecosystem functioning, human health and economies has increased dramatically over the last decades. Discoveries of invasive pests and pathogens previously unknown to science or with unknown host associations yet damaging on novel hosts highlights the necessity of developing novel tools to predict their appearance in hitherto naïve environments. The use of sentinel plant systems is a promising tool to improve the detection of pests and pathogens before introduction and to provide valuable information for the development of preventative measures to minimize economic or environmental impacts. Though sentinel plantings have been established and studied during the last decade, there still remains a great need for guidance on which tools and protocols to put into practice in order to make assessments accurate and reliable. The sampling and diagnostic protocols chosen should enable as much information as possible about potential damaging agents and species identification. Consistency and comparison of results are based on the adoption of common procedures for sampling design and sample processing. In this paper, we suggest harmonized procedures that should be used in sentinel planting surveys for effective sampling and identification of potential pests and pathogens. We also review the benefits and limitations of various diagnostic methods for early detection in sentinel systems, and the feasibility of the results obtained supporting National Plant Protection Organizations in pest and commodity risk analysis.
Keywords: alien invasive pests, alien invasive pathogens, commodity risk analysis, early warning, sampling techniques, sentinel plants, pest risk analysis, prediction
Published in DiRROS: 01.07.2019; Views: 2449; Downloads: 1447
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8. Ocenjevanje razlik v fenološkem razvoju dreves v nižinskem poplavnem gozdu na podlagi satelitskih posnetkovDavid Hladnik, 2018, original scientific article Abstract: Na območju Krakovskega pragozdnega rezervata smo ocenjevali fenološke razlike prevladujočih drevesnih vrst na podlagi satelitskih posnetkov Sentinel-2. Ocenili smo vrednosti normiranega diferencialnega vegetacijskega indeksa NDVI v obdobju med 29. marcem in 5. oktobrom 2017. Razlike v fenološkem razvoju doba, belega gabra in črne jelše smo potrdili s štirimi zaporednimi satelitskimi posnetki v aprilu in maju. Ocene NDVI iz tretje dekade aprila, druge in tretje dekade v maju 2017 je bilo mogoče uporabiti za razlikovanje razvoja najzgodnej- šega olistanja belega gabra, kasnejšega olistanja doba in in poznega končnega olistanja črne jelše. S primerjavo vzorčnih ploskev v dobovih sestojih je mogoče sklepati o mikrorastiščnih razlikah, ki vplivajo tudi na oceno vegetacijskih indeksov.
Keywords: fenološki razvoj dreves, NDVI, Sentinel-2, Krakovski gozd
Published in DiRROS: 22.05.2018; Views: 3530; Downloads: 785
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