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Query: "author" (Roman A. Li) .

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41.
Triangular in vivo self-assembling coiled-coil protein origami
Sabina Božič Abram, Helena Gradišar, Jana Aupič, Adam Round, Roman Jerala, 2021, original scientific article

Keywords: coiled coil, enzyme clustering, biosynthesis, resveratrol, mevalonate
Published in DiRROS: 22.03.2021; Views: 1722; Downloads: 1017
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42.
Decrease in cellular nanovesicles concentration in blood of athletes more than 15 hours after marathon
Zala Jan, Mitja Drab, Damjana Drobne, Apolonija Bedina Zavec, Mojca Benčina, Barbara Drašler, Matej Hočevar, Judita Lea Krek, Ljubiša Pađen, Manca Pajnič, Neža Repar, Boštjan Šimunič, Roman Štukelj, Veronika Kralj-Iglič, 2021, original scientific article

Abstract: Introduction: Cellular nanovesicles (CNVs), that are shed from cells, have been recognized as promising indicators of health status. We analyzed the effect of long-distance running on concentration of CNVs, along with some standard blood parameters, in 27 athletes two days before and > 15 hours after physical effort. Methods: CNVs were isolated by repetitive centrifugation and washing of samples, and assessed by flow cytometry. Cholinesterase (ChE) and glutathione S-transferase (GST) activity were measured spectrophotometrically. Interleukin 6 (IL-6) and tumor necrosis factor-% (TNF-%) concentrations were measured using enzyme-linked immunosorbent assay (ELISA). C-reactive protein (CRP) was measured with immunoturbidimetric determination and lipidogram parameters were measured by enzymatic colorimetric assay. Flow cytometry was used for blood cell count and mean platelet volume (MPV) measurement. Results: More than 15 hours after physical effort a decrease was found in CNVs% concentration in isolates from blood (46%; p< 0.05), in ChE activity in whole blood (47%; p< 0.001), in plasma (34%; p< 0.01), and in erythrocyte suspension (54%; p< 0.001), as well as in GST activity in erythrocyte suspension (16%; p< 0.01) and in IL-6 concentration in plasma (63%; p< 0.05). We found no change in GST activity in plasma and in TNF-% concentration in plasma. Correlations (> 0.8; p< 0.001) between CNVs% concentration and ChE activity, and GST activity, respectively, in erythrocyte suspension were found. Conclusion: We found that > 15 hours post-physical effort, CNVs% concentration was below the initial value, concomitant with other measured parameters: ChE and GST activity as well as IL-6 concentration, indicating a favorable effect of physical effort on health status. CNVs% concentration and ChE activity in isolates from peripheral blood proved to have potential as indicators of the response of the human body to inflammation after physical effort. Physical activity should be considered as an important factor in preparation of subjects for blood sampling in procedures focusing on CNV-containing diagnostic and therapeutic compounds.
Keywords: membrane vesiculation, physical effort, blood samples, inflammation process, cellular nanovesicles, marathon
Published in DiRROS: 25.01.2021; Views: 1519; Downloads: 4903
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43.
Platformne storitve
Ana Robnik, Andrej Ciglič, Aleš Balanč, Dušan Gabrijelčič, Jan Porekar, Arso Savanović, Polona Škraba, Roman Kužnar, Ignac Zupan, 2015, published scientific conference contribution

Published in DiRROS: 08.12.2020; Views: 1448; Downloads: 433
.pdf Full text (608,68 KB)

44.
Engineering and rewiring of a calcium-dependent signaling pathway
Maja Meško, Tina Lebar, Petra Dekleva, Roman Jerala, Mojca Benčina, 2020, original scientific article

Published in DiRROS: 25.11.2020; Views: 1682; Downloads: 1050
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Sensitivity analysis, calibration and validation of a phenology model for Pityogenes chalcographus (CHAPY)
Nikica Ogris, Mitja Ferlan, Tine Hauptman, Roman Pavlin, Andreja Kavčič, Maja Jurc, Maarten De Groot, 2020, original scientific article

Abstract: A phenology model of Pityogenes chalcographus was developed. The model quite accurately simulates the seasonal dynamics of P. chalcographus. Sensitivity analysis revealed the most influential parameters. CHAPY was calibrated and validated for Slovenia. Development of the model revealed several knowledge gaps.
Keywords: six-toothed spruce bark beetle, insect outbreak, population dynamics, voltinism, ecological modelling, pheromone trap, trap tree, monitoring
Published in DiRROS: 03.06.2020; Views: 2265; Downloads: 1291
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Sistemski pogled na izkušnjo raka in zdravljenja v otroštvu
Roman Korenjak, 1998, published professional conference contribution

Published in DiRROS: 17.09.2019; Views: 1686; Downloads: 459
.pdf Full text (219,94 KB)

50.
Informacije in napotki za bolnike, svojce in obiskovalce
2011, dictionary, encyclopaedia, lexicon, manual, atlas, map

Abstract: V pričujoči knjižici smo na enem mestu združili vse pomembne informacije, ki naj bolnikom, pa tudi njihovim svojcem ali spremljevalcem, olajšajo prihod, gibanje in bivanje na inštitutu. Pomembno je, da vsak bolnik čimprej in kar se da brez ovir pride do svojega zdravnika, medicinske sestre, radiološkega inženirja ali kateregakoli drugega zdravstvenega delavca, ki ga v tistem trenutku potrebuje. Vsem bolnikom in obiskovalcem želimo, da bi se pri nas dobro počutili, pri tem pa naj jim bo ta knjižica v pomoč.
Published in DiRROS: 25.03.2019; Views: 1496; Downloads: 337
.pdf Full text (299,54 KB)

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