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4. Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CTSebastijan Rep, Luka Ležaič, Tomaž Kocjan, Marija Pfeifer, Mojca Jensterle Sever, Urban Simončič, Petra Tomše, Marko Hočevar, 2015, original scientific article Keywords: lesions representing enlarged parathyroid tissue, triple-phase, standardized uptake value, retention index, lesion contrast, rak (medicina), obščitnični adenomi, diagnostika Published in DiRROS: 22.04.2024; Views: 249; Downloads: 261 Full text (850,44 KB) This document has many files! More... |
5. How beech provenance affects the structure of secondary xylem, leaf traits, and the ectomycorrhizal community under optimal growth conditionsTanja Mrak, Jožica Gričar, Tina Unuk Nahberger, Gregor Božič, Luka Krajnc, Peter Prislan, Domen Arnič, Tom Levanič, Hojka Kraigher, 2024, original scientific article Abstract: Beyond growth parameters and drought tolerance, comparatively little is known about the functioning of different beech (Fagus sylvatica L.) provenances. We investigated properties of leaves, stem secondary xylem, and ectomycorrhiza (ECM), and explored their interdependencies to identify the best performing beech provenance in optimal growth conditions. The study was conducted on 23-year-old trees in a provenance trial. The investigated provenances originated from Atlantic (Belgium—BE), Alpine (Italy—IT, Slovenia—SI), and continental climates (the Czech Republic—CZ). A significant effect of provenance was observed for stem vessel diameters and conductive area, as well as for foliar %C, δ13C, δ15N, and δ18O. δ13C as a proxy of intrinsic water use efficiency (iWUE) showed that the highest iWUE was achieved in BE provenance. Individuals with a better iWUE had wider growth rings regardless of provenance. Better iWUE was associated with lower specific leaf area (SLA). ECM community composition and diversity indices did not differ significantly among the provenances. Specific ECM taxa were associated with individuals with high SLA, δ13C, δ15N, and δ18O. In optimal growth conditions with no stress events, BE is a promising provenance due to an efficient water conducting system with high vessel diameters and conductive area, and high iWUE, while Alpine provenances showed an adaptation of their water conducting system to freezing conditions at their original locations. Integrating findings from different compartments improves our understanding of functioning of different beech provenances. Keywords: Fagus sylvatica, provenance trial, stable isotopes, specific leaf area, xylem vessels, ectomycorrhizal fungi Published in DiRROS: 19.04.2024; Views: 157; Downloads: 662 Full text (2,11 MB) This document has many files! More... |
6. Aggressive anticancer treatment in the last 2 weeks of lifeNena Golob, Teja Oblak, Luka Čavka, Maša Kušar, Boštjan Šeruga, 2024, original scientific article Abstract: Background: There is a concern that terminally ill cancer patients may be aggressively treated due to the rapidly growing possibilities of anticancer treatment. The aim of this study was to evaluate the use of anticancer treatment at the end of life (EoL). Materials and methods: This retrospective study included adult patients with advanced solid cancers who were treated at the Institute of Oncology Ljubljana and died of cancer between January 2015 and December 2019. A multiple logistic regression model was used to assess an association between the aggressiveness of anticancer treatment (i.e. systemic therapy, radiotherapy and surgery) in the last 2 weeks of life and year of death, age at death, sex, prognosis of cancer and enrolment into the specialist palliative care (SPC). Results: We included 1736 patients in our analysis. Overall, 13.7% of patients were enrolled into the SPC and 14.4% received anticancer treatment in the last 2 weeks of life. The odds of receiving anticancer treatment significantly increased over time [odds ratio (OR) 1.15, 95% confidence interval (CI) 1.04-1.27]. There was an increased use of novel systemic therapy (e.g. small-molecule targeted therapy and immunotherapy) at the EoL. Older patients had significantly lower odds to receive anticancer treatment in the last 2 weeks of life as compared to younger patients (OR 0.96, 95% CI 0.95-0.98). As compared to patients receiving only a standard oncology care, those also enrolled into the SPC had significantly lower odds for anticancer treatment in the last 2 weeks of life (OR 0.22, 95% CI 0.12-0.43). Conclusions: Terminally ill cancer patients have increased odds for receiving anticancer treatment, especially novel systemic therapies, in the last 2 weeks of life. Younger patients and those not enrolled into the SPC are at particular risk for anticancer treatment at the EoL Keywords: systemic therapy, aggressive treatment, anticancer drugs, palliative care Published in DiRROS: 18.04.2024; Views: 124; Downloads: 70 Full text (335,97 KB) This document has many files! More... |
7. Enhancing balance in Parkinson’s disease patients : a comprehensive literature review on the efficacy of exercise in an enriched environmentAna Ponebšek, Friderika Kresal, Luka Šlosar, 2023, review article Abstract: Various physiotherapeutic methods and approaches play a significant role in the
treatment of patients with Parkinson’s disease, including the use of enriched environments. Virtual reality (VR) as a type of enriched environment has the potential to create
multiple sensory experiences and feedback, influencing various aspects of the patient’s
information processing and response. The suitability for home use and the considerable impact on motivation highlight its advantages over alternative approaches. The
objective of this review is to investigate the impact of VR-based exercise on balance
outcomes among individuals with Parkinson’s disease. The inclusion criteria consisted Parkinson’s disease. The comparable improvements in balance observed between the
experimental and control groups signify the potential effectiveness of VR-based exercises. This underscores the encouragement for further development in this technology,
particularly focusing on fully immersive VR environments, which may yield superior
effects in enhancing balance among individuals with Parkinson’s disease.
of randomized controlled trials (RCTs) that examined the effects of exercise in a VR
environment on individuals’ static and dynamic balance outcomes. In order to gather
relevant studies, we conducted a comprehensive search across three databases. From a
dataset of 625 records, we conducted a comprehensive full-text screening based on specific inclusion and exclusion criteria. This process resulted in the inclusion of 14 RCTs
in our review. The emerging evidence regarding exercising in a VR environment does
not definitively prove its superiority over standard exercise routines. However, studies
have demonstrated that both the experimental and control groups showed comparable improvements in enhancing static and dynamic balance among individuals with Keywords: virtual reality, Parkinson's disease, balance, rehabilitation Published in DiRROS: 16.04.2024; Views: 129; Downloads: 53 Full text (552,71 KB) This document has many files! More... |
8. Wandering domains arising from Lavaurs maps with Siegel disksMatthieu Astorg, Luka Boc Thaler, Han Peters, 2023, original scientific article Abstract: The first example of polynomial maps with wandering domains was constructed in 2016 by the first and last authors, together with Buff, Dujardin and Raissy. In this paper, we construct a second example with different dynamics, using a Lavaurs map with a Siegel disk instead of an attracting fixed point. We prove a general necessary and sufficient condition for the existence of a trapping domain for nonautonomous compositions of maps converging parabolically towards a Siegel-type limit map. Constructing a skew-product satisfying this condition requires precise estimates on the convergence to the Lavaurs map, which we obtain by a new approach. We also give a self-contained construction of parabolic curves, which are integral to this new method. Keywords: Fatou sets, holomorphic dynamics, parabolic implosion, polynomial mappings, skew-products, wandering Fatou components, parabolic curves, nonautonomous dynamics Published in DiRROS: 09.04.2024; Views: 213; Downloads: 59 Full text (1,55 MB) This document has many files! More... |
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