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Abstract: Satellite observations of sea surface temperature (SST) are essential for accurate weather forecasting and climate modeling. However, these data often suffer from incomplete coverage due to cloud obstruction and limited satellite swath width, which requires development of dense reconstruction algorithms. The current state of the art struggles to accurately recover high-frequency variability, particularly in SST gradients in ocean fronts, eddies, and filaments, which are crucial for downstream processing and predictive tasks. To address this challenge, we propose a novel two-stage method CRITER (Coarse Reconstruction with ITerative Refinement Network), which consists of two stages. First, it reconstructs low-frequency SST components utilizing a Vision Transformer-based model, leveraging global spatio-temporal correlations in the available observations. Second, a UNet type of network iteratively refines the estimate by recovering high-frequency details. Extensive analysis on datasets from the Mediterranean, Adriatic, and Atlantic seas demonstrates CRITER's superior performance over the current state of the art. Specifically, CRITER achieves up to 44 % lower reconstruction errors of the missing values and over 80 % lower reconstruction errors of the observed values compared to the state of the art.
Keywords: deep learning, reconstruction algorithms, satellite measurements
Published in DiRROS: 14.10.2025; Views: 265; Downloads: 127
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Abstract: Purpose Patients with multiple myeloma (MM) develop osteolytic lesions with fractures, pain, and impaired quality of life. Preclinical data show an anabolic effect of loading exercise in osteolytic lesions of MM. This 6-month pilot study evaluated feasibility and safety of impact-loading exercise in patients with MM after assessment of spinal stability. Methods We assigned 20 patients to perform 45 min of guided impact-loading exercise twice a week and home-based training once a week or stretching exercise twice a week. Primary endpoint was assessment of feasibility and safety. Secondary endpoints were assessments of physical performance, quality of life, and bone remineralization. Results Of 77 eligible patients with MM, 26% accepted participation. In the impact group, 9/12 and in the stretching group 7/8 patients completed training with adherence rates of 65.8 and 81.1%. Ninety percent of the stamping and jumping exercises were performed with increasing intensity from the prescribed training volume of ≥ 100%. Low severity pain events were reported after 32.9% of impact sessions. No serious adverse events were observed. After 6 months, 6-minute walk distance increased in the impact group by 35 m and in the stretching group by 46 m, and chair-rise test improved in the stretching group by 1.7 s. Global health status increased by 24.9% in the impact group, and functional scale by 31.9% in the stretching group based upon EORTC QLQ-C30. No signs of bone remineralization were observed in computed tomography. Conclusion Impact training is feasible and appears to be safe in selected MM patients.
Keywords: multiple myeloma, feasibility, safety, impact-loading exercise, bone turnover maker
Published in DiRROS: 13.10.2025; Views: 202; Downloads: 96
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Abstract: The interconnected nature of orofacial, neck musculature, and the neural system suggests that localised19activities, such as teeth clenching, can influence remote spinal excitability. While stretching exercises are20known to have both local and remote effects, the specific impact of orofacial muscle stretching remains21underexplored. This study investigates the effects of two interventions: 25 guided orofacial and neck22stretching and mobility exercises (Exercises), and chewing six chewing gums for six minutes (Chewing),23on the soleus H-reflex and D1 presynaptic inhibition. Ten volunteers (mean age: 28.75 ± 9 years)24participated, with H-reflex measurements collected using high-density electromyography (HDsEMG)25before and after each intervention. Latency (HLAT ), duration (H DUR ), peak-to-peak (H P2P, D1 PSP ) and positive26peak (H POS ) amplitudes were extracted from unconditioned and conditioned H-reflexes. The ratio27(D1 P2P/H P2P) between conditioned (D1 P2P ) and unconditioned (H P2P ) H-reflex was calculated to study the28D1 presynaptic inhibition mechanisms. Additionally, 8,400 firings from 376 distinct motor units (MUs),29categorised by firing threshold were analysed for latency, firing ratio, and inhibition probability (D1 PROB ).30HP2P, HPOS decreased and HDUR was significantly increased after the Exercise intervention, while the31Chewing intervention had no effect on these parameters. The D1 P2P/H P2P ratio and D1 PROB remained32unchanged, suggesting that the observed drop in H P2P is not mediated by presynaptic inhibition33mechanisms. Single MU analysis confirmed the H-reflex findings. The results of this study suggest that34stretching and mobility exercises targeting the neck and orofacial region can reduce neuromuscular35excitability, offering potential for non-pharmacological management of conditions associated with36motoneuron hyperexcitability and general whole-body relaxation
Keywords: high-density electromyography (HDsEMG), remote effect, stretching
Published in DiRROS: 13.10.2025; Views: 216; Downloads: 105
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Abstract: This paper presents some of Santorio’s marginalia to his Commentaria in primam fen primi libri Canonis Avicennae (Venice, 1625), which I identified in the Sloane Collection of the British Library in 2016, as well as the evidence for their authorship. The name of the Venetian physician Santorio Santori (1561–1636) is linked with the introduction of quantification in medicine and with the invention of precision instruments that, displayed for the first time in this work, laid down the foundations for what we today understand as evidence-based medicine. But Santorio’s monumentale opus also contains evidence of many quantified experiments and displays his ideas on mixtures, structure of matter and corpuscles, which are in many cases clarified and completed by the new marginalia. These ideas testify to an early interest in chemistry within the Medical School of Padua which predates both Galileo and Sennert and which has hitherto been unknown.
Keywords: quantification in medicine, marginalia, corpuscular theory, early modern chemistry
Published in DiRROS: 13.10.2025; Views: 188; Downloads: 61
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Keywords: varstvo gozdov, morfološke analize
Published in DiRROS: 10.10.2025; Views: 224; Downloads: 0
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