Presejanje - iskanje mutacij v tumorskem supresorskem genu Tp53 z uporabo DGGEin sekveniranja

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Title:	Presejanje - iskanje mutacij v tumorskem supresorskem genu Tp53 z uporabo DGGEin sekveniranja
Authors:	ID Ličar, Alenka (Author) ID Novaković, Srdjan (Author)
Files:	PDF - Presentation file, download (283,94 KB) MD5: F5E0B6BD31672219F83A662C477EE807 PID: 20.500.12556/dirros/d3eea42d-1d7b-4524-98da-c10e0ff7c440
Language:	Slovenian
Typology:	1.03 - Other scientific articles
Organization:	OI - Institute of Oncology
Abstract:	Mutacije v genu Tp53 so dokazane pri več kot 50 % malignih bolezni. Pri številnih malignih bolezni je vloga mutacij v tem genu neposredno povezana z nastankom raka. Namen našega prispevka je posredovati informacijo o metodoloških pristopih, s katerimi določamo mutacije v genu Tp53 na Oddelku za molekularno diagnostiko Onkološkega inštituta Ljubljana.
Publication status:	Published
Publication version:	Version of Record
Year of publishing:	2008
Number of pages:	str. 122-124
Numbering:	Letn. 12, št. 2
PID:	20.500.12556/DiRROS-8852
UDC:	616-006
ISSN on article:	1408-1741
URN:	URN:NBN:SI:doc-RSF8HEVG
COBISS.SI-ID:	25340121
Copyright:	by Authors
Note:	BSDOCID143384;
Publication date in DiRROS:	31.08.2018
Views:	3199
Downloads:	744
Metadata:
:	LIČAR, Alenka and NOVAKOVIĆ, Srdjan, 2008, Presejanje - iskanje mutacij v tumorskem supresorskem genu Tp53 z uporabo DGGEin sekveniranja. Onkologija [online]. 2008. Vol. 12, no. 2, p. 122–124. [Accessed 15 March 2025]. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=8852 Copy citation

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License:	CC BY 4.0, Creative Commons Attribution 4.0 International

Link:	http://creativecommons.org/licenses/by/4.0/
Description:	This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:	31.08.2018

Language:	English
Title:	Screening for Mutations in Tp53 Tumor Suppressor Gene using DGGE and Sequencing
Abstract:	Mutations in the T53 gene have been detected in more than 50% of different malignancies. The development of many of these diseases is directly associated with the mutations in the Tp53 gene. The aim of this article is to provide information about new methods that have been introduced into our Department of Molecular Diagnostics at the Institute of Oncology Ljubljana for scanning mutations in the Tp53 gene.