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Naslov:Thyroid lesions incidentally detected by [sup] 18F-FDG PET-CT : a two centre retrospective study
Avtorji:ID Jamšek, Jan (Avtor)
ID Žagar, Ivana (Avtor)
ID Gaberšček, Simona (Avtor)
ID Grmek, Marko (Avtor)
Datoteke:.pdf PDF - Predstavitvena datoteka, prenos (654,61 KB)
MD5: EC6CC34C46D0177FCC0443C3D49FFC02
 
Jezik:Angleški jezik
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:Logo OI - Onkološki inštitut Ljubljana
Povzetek:Incidental 18F-FDG uptake in the thyroid on PET-CT examinations represents a diagnostic challenge. The maximal standardized uptake value (SUVmax) is one possible parameter that can help in distinguishing between benign and malignant thyroid PET lesions. We retrospectively evaluated 18F-FDG PET-CT examinations of 5,911 patients performed at two different medical centres from 2010 to 2011. If pathologically increased activity was accidentally detected in the thyroid, the SUVmax of the thyroid lesion was calculated. Patients with incidental 18F-FDG uptake in the thyroid were instructed to visit a thyroidologist, who performed further investigation including fine needle aspiration cytology (FNAC) if needed. Lesions deemed suspicious after FNAC were referred for surgery. Incidental 18F-FDG uptake in the thyroid was found in 3.89% - in 230 out of 5,911 patients investigated on PET-CT. Malignant thyroid lesions (represented with focal thyroid uptake) were detected in 10 of 66 patients (in 15.2%). In the first medical centre the SUVmax of 36 benign lesions was 5.6 +- 2.8 compared to 15.8 +- 9.2 of 5 malignant lesions (p < 0.001). In the second centre the SUVmax of 20 benign lesions was 3.7 +- 2.2 compared to 5.1 +- 2.3 of 5 malignant lesions (p = 0.217). All 29 further investigated diffuse thyroid lesions were benign. Incidental 18F-FDG uptake in the thyroid was found in 3.89% of patients who had a PET-CT examination. Only focal thyroid uptake represented a malignant lesion in our study - in 15.2% of all focal thyroid lesions. SUVmax should only serve as one of several parameters that alert the clinician on the possibility of thyroid malignancy.
Ključne besede:thyroid cancer, PET incidentaloma, PET-CT
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Datum objave:01.06.2015
Založnik:Association of Radiology and Oncology
Leto izida:2015
Št. strani:str. 121-127, II
Številčenje:Vol. 49, no. 2
Izvor:Ljubljana
PID:20.500.12556/DiRROS-18790 Novo okno
UDK:616-006
ISSN pri članku:1318-2099
DOI:10.2478/raon-2014-0039 Novo okno
COBISS.SI-ID:2185388 Novo okno
Avtorske pravice:by Authors
Datum objave v DiRROS:22.04.2024
Število ogledov:627
Število prenosov:200
Metapodatki:XML DC-XML DC-RDF
:
JAMŠEK, Jan, ŽAGAR, Ivana, GABERŠČEK, Simona in GRMEK, Marko, 2015, Thyroid lesions incidentally detected by [sup] 18F-FDG PET-CT : a two centre retrospective study. Radiology and oncology [na spletu]. 2015. Vol. 49, no. 2, p. 121–127, ii. [Dostopano 6 april 2025]. DOI 10.2478/raon-2014-0039. Pridobljeno s: https://dirros.openscience.si/IzpisGradiva.php?lang=slv&id=18790
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Gradivo je del revije

Naslov:Radiology and oncology
Skrajšan naslov:Radiol. oncol.
Založnik:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 Novo okno

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Jezik:Slovenski jezik
Naslov:Thyroid lesions incidentally detected by 18F-FDG PET-CT


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