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Title:Thyroid lesions incidentally detected by [sup] 18F-FDG PET-CT : a two centre retrospective study
Authors:ID Jamšek, Jan (Author)
ID Žagar, Ivana (Author)
ID Gaberšček, Simona (Author)
ID Grmek, Marko (Author)
Files:.pdf PDF - Presentation file, download (654,61 KB)
MD5: EC6CC34C46D0177FCC0443C3D49FFC02
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:Incidental 18F-FDG uptake in the thyroid on PET-CT examinations represents a diagnostic challenge. The maximal standardized uptake value (SUVmax) is one possible parameter that can help in distinguishing between benign and malignant thyroid PET lesions. We retrospectively evaluated 18F-FDG PET-CT examinations of 5,911 patients performed at two different medical centres from 2010 to 2011. If pathologically increased activity was accidentally detected in the thyroid, the SUVmax of the thyroid lesion was calculated. Patients with incidental 18F-FDG uptake in the thyroid were instructed to visit a thyroidologist, who performed further investigation including fine needle aspiration cytology (FNAC) if needed. Lesions deemed suspicious after FNAC were referred for surgery. Incidental 18F-FDG uptake in the thyroid was found in 3.89% - in 230 out of 5,911 patients investigated on PET-CT. Malignant thyroid lesions (represented with focal thyroid uptake) were detected in 10 of 66 patients (in 15.2%). In the first medical centre the SUVmax of 36 benign lesions was 5.6 +- 2.8 compared to 15.8 +- 9.2 of 5 malignant lesions (p < 0.001). In the second centre the SUVmax of 20 benign lesions was 3.7 +- 2.2 compared to 5.1 +- 2.3 of 5 malignant lesions (p = 0.217). All 29 further investigated diffuse thyroid lesions were benign. Incidental 18F-FDG uptake in the thyroid was found in 3.89% of patients who had a PET-CT examination. Only focal thyroid uptake represented a malignant lesion in our study - in 15.2% of all focal thyroid lesions. SUVmax should only serve as one of several parameters that alert the clinician on the possibility of thyroid malignancy.
Keywords:thyroid cancer, PET incidentaloma, PET-CT
Publication status:Published
Publication version:Version of Record
Publication date:01.06.2015
Publisher:Association of Radiology and Oncology
Year of publishing:2015
Number of pages:str. 121-127, II
Numbering:Vol. 49, no. 2
Source:Ljubljana
PID:20.500.12556/DiRROS-18790 New window
UDC:616-006
ISSN on article:1318-2099
DOI:10.2478/raon-2014-0039 New window
COBISS.SI-ID:2185388 New window
Copyright:by Authors
Publication date in DiRROS:22.04.2024
Views:637
Downloads:203
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JAMŠEK, Jan, ŽAGAR, Ivana, GABERŠČEK, Simona and GRMEK, Marko, 2015, Thyroid lesions incidentally detected by [sup] 18F-FDG PET-CT : a two centre retrospective study. Radiology and oncology [online]. 2015. Vol. 49, no. 2, p. 121–127, ii. [Accessed 11 April 2025]. DOI 10.2478/raon-2014-0039. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=18790
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Title:Thyroid lesions incidentally detected by 18F-FDG PET-CT


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