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Title:Cisplatin-induced non-convulsive posterior reversible encephalopathy syndrome in a 41-year-old woman with metastatic malignant melanoma
Authors:ID Ocvirk, Janja (Author)
ID Boc, Marko (Author)
ID Reberšek, Martina (Author)
ID Roš-Opaškar, Tanja (Author)
Files:.pdf PDF - Presentation file, download (343,74 KB)
MD5: 0E149723EF9814F4AC9283AF96A03229
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:Background. Cisplatin, a widely used antineoplastic agent usually induces peripheral neuropathy, but can rarely also complicate with encephalopathy, with or without seizures. Case report. We report a case of a young patient with metastatic malignant melanoma with signs and symptoms of cisplatin-induced non-convulsive posterior reversible encephalopaty syndrome. Within the days shortly after the first cycle of cisplatin based chemotherapy the patient suffered from nausea, vomitus, headache, severe pain at the site of sub-cutaneous metastases and confusion. She later experienced somnolence, cortical blindness and aphasia, but without epileptic seizures. Conclusions. Cisplatin is an effective chemotherapeutic drug but also very toxic one and physicians using it must also be aware of possible encephalopathy.
Publication status:Published
Publication version:Version of Record
Publication date:01.01.2009
Publisher:Association of Radiology and Oncology
Year of publishing:2009
Number of pages:str. 120-125
Numbering:Vol. 43, no. 2
Source:Ljubljana
PID:20.500.12556/DiRROS-18357 New window
UDC:616.5-006.6-085:616.831
ISSN on article:1318-2099
DOI:10.2478/v10019-009-0005-0 New window
COBISS.SI-ID:711547 New window
Copyright:by Authors
Publication date in DiRROS:08.03.2024
Views:123
Downloads:36
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

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