| Title: | Antifungal effect of polymethyl methacrylate resin base with embedded Au nanoparticles |
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| Authors: | ID Marić, Ivan (Author)
ID Zore, Anamarija (Author)
ID Rojko, Franc (Author)
ID Sever Škapin, Andrijana (Author)
ID Štukelj, Roman (Author)
ID Učakar, Aleksander (Author)
ID Vidrih, Rajko (Author)
ID Veselinović, Valentina (Author)
ID Gotić, Marijan (Author)
ID Bohinc, Klemen (Author) |
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| Files: |  URL - Source URL, visit https://www.mdpi.com/2079-4991/13/14/2128
 PDF - Presentation file, download (2,90 MB)
MD5: 386583CA72B949412B78EDE65C534265
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  ZAG - Slovenian National Building and Civil Engineering Institute
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| Abstract: | Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how well Candida albicans adheres to a polymethyl methacrylate (PMMA) resin base with gold (Au) nanoparticles. We synthesized Au nanoparticles and characterized them. The average size of Au nanoparticles embedded in PMMA was 11 nm. The color difference ∆E between PMMA and PMMA/Au composites was 2.7 and was still esthetically acceptable to patients. PMMA/Au surfaces are rougher and more hydrophilic than pure PMMA surfaces, and the isoelectric point of both types of surfaces was 4.3. Above the isoelectric point, PMMA/Au surfaces are more negatively charged than PMMA surfaces. The added Au nanoparticles decreased the tensile strength, while the hardness did not change significantly. Adhesion measurements showed that PMMA surfaces modified with Au nanoparticles reduced the extent of microbial adhesion of Candida albicans. |
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| Keywords: | fungal adhesión, C. albicans, polymethyl methacrylate resin, Au, surface properties, composites |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 22.07.2023 |
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| Publisher: | MDPI AG |
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| Year of publishing: | 2023 |
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| Number of pages: | 15 str. |
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| Numbering: | Vol. 13, iss. 14, [article no.] 2128 |
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| PID: | 20.500.12556/DiRROS-16721  |
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| UDC: | 66 |
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| ISSN on article: | 2079-4991 |
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| DOI: | 10.3390/nano13142128 |
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| COBISS.SI-ID: | 159528707 |
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| Copyright: | © 2023 by the authors. Licensee MDPI, Basel, Switzerland |
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| Note: | Nasl. z nasl. zaslona;
Soavtorji: Anamarija Zore, Franc Rojko, Andrijana Sever Škapin, Roman Štukelj, Aleksander Učakar, Rajko Vidrih, Valentina Veselinović, Marijan Gotić and Klemen Bohinc;
Opis vira z dne 24. 7. 2023;
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| Publication date in DiRROS: | 24.07.2023 |
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| Views: | 359 |
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| Downloads: | 141 |
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