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Query: "author" (Šereg Bahar Maja) .

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1.
Higher levels of total pepsin and bile acids in the saliva as a possible risk factor for early laryngeal cancer
Maja Šereg Bahar, Aleš Jerin, Irena Hočevar-Boltežar, 2015, original scientific article

Abstract: Background. Gastroesophageal reflux is suspected to be an etiological factor in laryngeal and pharyngeal cancer. The aim of this study was to establish, using a non-invasive method, whether laryngopharyngeal reflux (LPR) appears more often in patients with early laryngeal cancer than in a control group. Patients and methods. We compared the pH, the level of bile acids, the total pepsin and the pepsin enzymatic activity in saliva in a group of 30 patients with T1 laryngeal carcinoma and a group of 34 healthy volunteers. Results. The groups differed significantly in terms of levels of total pepsin and bile acids in the saliva sample. Higher levels of total pepsin and bile acids were detected in the group of cancer patients. No significant impact of other known factors influencing laryngeal mucosa (e.g. smoking, alcohol consumption, and the presence of irritating substances in the workplace) on the results of saliva analysis was found. Conclusions. A higher level of typical components of LPR in the saliva of patients with early laryngeal cancer than in the controls suggests the possibility that LPR, especially biliary reflux, has a role in the development of laryngeal carcinoma.
Keywords: laryngopharyngeal reflux, gastric acid, pepsin, bile acids, laryngeal carcinoma
Published in DiRROS: 17.04.2024; Views: 169; Downloads: 98
.pdf Full text (558,42 KB)

2.
Anatomija in fiziologija zgornjega dela dihal in prebavil
Maja Šereg Bahar, 2022, published professional conference contribution

Abstract: Zgornja dihala in prebavila tvorijo: zunanje, srednje in notranje uho, nosni organ, ustna votlina, zgornje, srednje in spodnje žrelo ter grlo. Nekateri med zgornja prebavila štejejo tudi požiralnik. V tem predelu najdemo še ščitnico, obščitnice ter žleze slinavke. Ti organi so sestavljeni iz različnih tkiv, iz katerih lahko vznika rak. To so: koža ter sluznice, ki jih pokriva večinoma ploščatocelični epitel, na nekaterih mestih respiratorni epitel, mišice, hrustanec, limfatično tkivo v žrelu in druga tkiva. Naloge zgornjih prebavil in dihal so: sluh in ravnotežje, dihanje, vohanje, žvečenje in požiranje ter začetek prebave hrane, tvorba glasu in govora, zaščitna – imunološka funkcija ter zaščita spodnjih dihal pred vdorom tekočine in hrane. Motorično in senzibilno oživčenje omogočajo možganski živci, arterijska preskrba poteka skozi arterije karotis interne in eksterne ter njunih vej. Drenaža limfe poteka skozi globoke in povrhnje vratne bezgavke, ki so številne. Venska kri odteka skozi venski pletež v veno jugularis.
Keywords: anatomija, fiziologija, zgornja dihala, zgornja prebavila
Published in DiRROS: 06.01.2023; Views: 543; Downloads: 178
.pdf Full text (75,64 KB)
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