1. Cognitive functioning in a cohort of high-grade glioma patientsAndreja Cirila Škufca Smrdel, Anja Podlesek, Marija Skoblar Vidmar, Jana Markovič, Jana Jereb, Manja Kuzma, Uroš Smrdel, 2023, original scientific article Abstract: High grade gliomas are associated with cognitive problems. The aim of the study was to investigate cognitive functioning in a cohort of patients with high grade glioma, according to isocitrate dehydrogenase (IDH) and methyl guanine methyl transferase (MGMT) status and other clinical characteristics. The patients with the high-grade glioma treated in Slovenia in given period of time were included in study. Postoperatively they completed neuropsychological assessment consisting of Slovenian Verbal Learning Test, Slovenian Controlled Oral Word Association Test, Trail Making Test Part A and B and self-evaluation questionnaire. We analysed results (z-scores and dichotomized results) also according to IDH mutation and MGMT methylation. We examined differences between groups using T-test, Mann-Whitney U, χ2 and Kendall's Tau tests. Out of 275 patients in the cohort, we included 90. Forty-six percent of patients were unable to participate due to poor performance status and other conditions related to tumour. Patients with the IDH mutation were younger, with better performance status, larger proportions of grade III tumours and MGMT methylation. In this group cognitive functioning is significantly better in the domains of immediate recall, short delayed recall and delayed recall, and in the fields of executive functioning and recognition. There were no differences in cognitive functioning in regard to MGMT status. Grade III tumours were associated with more frequent MGMT methylation. Self-assessment proved week tool, associated only with immediate recall. We found no differences in cognitive functioning according to MGMT status, but cognition was better when IDH mutation was present. In a cohort study of patients with high-grade glioma, almost half were unable to participate in a study, which points to an overrepresentation of patients with better cognitive functioning in the research. Keywords: cognition, high grade glioma, IDH1 mutation Published in DiRROS: 25.07.2024; Views: 222; Downloads: 78 Full text (649,88 KB) |
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3. Experiencing professional strains of nurses, radiation engineers and physicians working at the Institute of oncology in LjubljanaAndreja Cirila Škufca Smrdel, 2003, original scientific article Abstract: Background. Since 1974 the term burnout is used in psychology. Burnout describes the end result of stress and has been described by Maslach comprising three basic components: emotional exhaustion, depersonalization andlow personal accomplishment. In this paper we would like to describe some aspects of burnout experiences of the employees of the Institute of Oncology in Ljubljana. Subjects and methods. We used Questionnaire of professional stress, created by Zunter Nagy and Kocmur. In our research 137 health workers from four professional groups participated: physicians, graduated nurses, nurses and radiation engineers, representing 38% of all employees. Results. Wefound out that in the experience the professional stressof all four professional groups is relatively equalized. The most prominent feelings are of fatigue, irritability and work overload. There were no signs of depersonalization - as described by Maslach - reported in our group. In nursesand in radiation engineers a distress is significantly more often displayed due to poorer personal income and poorer material status. Nurses reported significantly more often the intention to change work position (51%),institution (57%) or job (47%). Conclusions. Workstress impacts on the experience and on the thought patterns in those participating in the study. Wecan describe those signs as burnout signs. However, there are more new questions opening in the future as well as the need to a longitudinal approachto the research of this more and more prominent field. Published in DiRROS: 06.02.2024; Views: 433; Downloads: 86 Full text (125,41 KB) |
4. Hodgkinov limfom : vodnik za bolnikeBarbara Jezeršek Novaković, Samo Zver, Metka Zajc, Aleksandra Grbič, Andreja Cirila Škufca Smrdel, Eda Vrtačnik-Bokal, Vesna Šalamun, Nina Kovačević, Lorna Zadravec-Zaletel, Matej Pečovnik, 2022, not set Keywords: rak (medicina), krvotvorne matične celice, transplantacija, psihološka pomoč, plodnost, hormonsko nadomestno zdravljenje Published in DiRROS: 24.07.2023; Views: 681; Downloads: 201 Full text (1,02 MB) |
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6. Kliničnopsihološka in psihiatrična obravnava v sklopu celostne obravnave bolnic z rakom dojk : izsledki iz pilotnega projekta celostne rehabilitacije OREHJana Jereb, Jana Knific, Jana Markovič, Tina Rus, Mateja Kurir-Borovčić, Nikola Bešić, Lorna Zadravec-Zaletel, Zlatka Mavrič, Anamarija Mozetič, Andreja Cirila Škufca Smrdel, 2022, published professional conference contribution abstract Keywords: onkologija, rak dojke, psihologija Published in DiRROS: 09.02.2023; Views: 908; Downloads: 188 Full text (39,03 KB) |
7. Vpliv onkološkega zdravljenja na nevrokognitivno funkcioniranjeAndreja Cirila Škufca Smrdel, 2022, published scientific conference contribution Abstract: Možganski tumorji so povezani z različnimi težavami v kognitivnem funkcioniranju, ki so odvisni od
dejavnikov bolezni, zdravljenja, pa tudi od osebnih dejavnikov bolnika. Kognitivno funkcioniranje ni le manifestacija bolezni, pač pa je tudi en od prognostičnih dejavnikov. Zato je ocenjevanje le-tega pomembno ne le v raziskavah, pač pa tudi pri celostni obravnavi bolnikov z možganskimi tumorji. Keywords: možganski tumorji, centralno živčevje, psihologija Published in DiRROS: 16.12.2022; Views: 687; Downloads: 169 Full text (131,55 KB) |
8. Priporočila za obravnavo bolnikov z rakom debelega črevesa in danke2020, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: rak debelega črevesa, rak danke, bolniki, zdravljenje Published in DiRROS: 18.03.2022; Views: 1175; Downloads: 641 Full text (1,30 MB) This document has many files! More... |
9. Klinična pot celostne rehabilitacije bolnikov z rakom dojkeNikola Bešić, Simona Borštnar, Andreja Gornjec, Teja Kovačec Hermann, Vesna Homar, Denis Mlakar-Mastnak, Nataša Kos, Nada Rotovnik-Kozjek, Mateja Kurir-Borovčić, Tanja Marinko, Andreja Cirila Škufca Smrdel, Branka Stražišar, Tanja Španić, Lorna Zadravec-Zaletel, 2020, final research report Keywords: rak dojke, bolniki, zdravljenje, klinične poti Published in DiRROS: 14.03.2022; Views: 1060; Downloads: 569 Full text (2,09 MB) This document has many files! More... |
10. Klinična pot celostne rehabilitacije bolnikov z rakom dojkeNikola Bešić, Simona Borštnar, Vesna Homar, Denis Mlakar-Mastnak, Zlatka Mavrič, Anamarija Mozetič, Jana Knific, Nataša Kos, Nina Kovačević, Nada Rotovnik-Kozjek, Nena Kopčavar Guček, Mateja Kurir-Borovčić, Tanja Marinko, Ana Pekle-Golež, Irena Rahne Otorepec, Gabrijela Simetinger, Andreja Cirila Škufca Smrdel, Branka Stražišar, Tanja Španić, Lorna Zadravec-Zaletel, 2021, final research report Keywords: rak dojke, bolniki, celostna rehabilitacija, klinične poti Published in DiRROS: 14.03.2022; Views: 1124; Downloads: 537 Full text (2,09 MB) This document has many files! More... |