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Title:Stranski učinki ob zdravljenju rakavih bolezni z zaviralci tirozinskih kinaz
Authors:ID Mencinger, Marina (Author)
Files:.pdf PDF - Presentation file, download (101,00 KB)
MD5: 34382BD994B3ABD81B63127E8CCDE5CE
 
Language:Slovenian
Typology:1.04 - Professional Article
Organization:Logo OI - Institute of Oncology
Abstract:Zaviralci tirozin-kinaz so multitarčna zdravila, ki prek zaviranja različnih celičnih procesov učinkujejo pri več vrstah rakavih boleznih. Čeprav so stranski učinki ob zaviralcih tirozinskih kinaz v splošnem prenosljivi, pa so lahko tudi resni in povzročajo nemalo preglavic bolnikom, ki prejemajo zdravila dolgotrajno. Pogosto je potrebno zmanjšanje odmerkov ali prehodna ukinitev, redkeje pa se odločimo za trajno prekinitev zdravljenja. Značilni so kožna toksičnost, kardiovaskularni zapleti, težave gastrointestinalnega trakta - predvsem diareja, nepravilno delovanje ščitnice in utrujenost ob zdravljenju rakave bolezni.
Keywords:tarčna zdravila, zaviralci tirozinskih kinaz, stranski učinki
Publication status:Published
Publication version:Version of Record
Year of publishing:2018
Number of pages:str. 24-27
Numbering:Letn. 22, št. 1
PID:20.500.12556/DiRROS-9222 New window
UDC:616-006
ISSN on article:1408-1741
DOI:10.25670/oi2018-004on New window
COBISS.SI-ID:2990971 New window
Copyright:by Authors
Publication date in DiRROS:26.10.2018
Views:3038
Downloads:768
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Record is a part of a journal

Title:Onkologija. strokovni časopis za zdravnike
Shortened title:Onkologija
Publisher:Onkološki inštitut
ISSN:1408-1741
COBISS.SI-ID:65324032 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:26.10.2018

Secondary language

Language:English
Title:Side effects of tyrosine kinase inhibitors in cancer treatment
Abstract:Tyrosine kinase inhibitors are multicentric drugs that inhibit different cellular processes and are effective in the treatment of many types of cancer. Although the side effects of tyrosine kinase inhibitors are generally tolerable, they may also be serious and cause numerous problems in patients receiving long-term medication. Dosage reductions or transient withdrawal are often required, but only rarely is the treatment permanently discontinued. Typical complications include skin toxicity, cardiovascular complications, problems in the gastrointestinal tract, in particular diarrhoea, thyroid malfunction, and treatment-specific fatigue. The present article lays out the most common side effects of treatment with tyrosine kinase inhibitors.
Keywords:targeted drugs, tyrosine kinase inhibitors, side effects


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