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Title:Vloga obsevanja pri zdravljenju raka danke
Authors:Velenik, Vaneja (Author)
Language:Slovenian
Tipology:1.08 - Published Scientific Conference Contribution
Organisation:Logo OI - Institute of Oncology
Abstract:Zdravljenje lokalno napredovalega raka danke je izrazito multidisciplinarno in zajema tako lokalno (operacijo in obsevanje) kot tudi sistemsko zdravljenje (kemoterapijo). V primerjavi z operativnim zdravljenjem samim, pooperativna radiokemoterapija statistično značilno izboljša lokalno kontrolo in preživetje bolnikov. Nemška randomizirana raziskava je potrdila prednost predoperativne radiokemoterapije pred pooperativnim zdravljenjem v smislu manjše akutne in pozne toksičnosti, boljše lokalne kontrole ter večjega deleža bolnikov z ohranjeno kontinuiteto črevesa. Še vedno pa ostaja nepojasnjena vrsta vprašanj, med katerimi so vloga kratkega predoperativnega obsevanja, vloga pooperativne kemoterapije po neoadjuvantnem zdravljenju, ali lahko tip operacije prilagodimo odgovoru tumorja na predoperativno zdravljenje, ali bi agresivnejše sistemsko zdravljenje izboljšalo izid bolezni in bi se lahko celo izognili zdravljenju z obsevanju. V prispevku je opisana vloga radioterapije v kombiniranem zdravljenju raka danke.
Keywords:obsevanje, radioterapija, rak danke, rak prebavil
Year of publishing:2013
COBISS_ID:1554299 Link is opened in a new window
UDC:616.3-006-08
ISSN on article:1408-1741
OceCobissID:1553275 Link is opened in a new window
URN:URN:NBN:SI:doc-99VB983L
Views:1967
Downloads:505
Files:.pdf PDF - Presentation file, download (310,18 KB)
 
Journal:Šola tumorjev prebavil, Ljubljana, 30. 11. 2012
Onkološki inštitut
 
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Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.08.2018

Secondary language

Language:English
Title:The role of irradiation in the treatment of rectal cancer
Abstract:Treatment of a locally-advanced rectal cancer is distinctively multidisciplinary and comprises both local (surgery and irradiation) and systemic treatment (chemotherapy). Compared to operative treatment alone, post-operative radio-chemotherapy statistically significantly improves local control and survival of patients. A German randomised study confirmed the advantage of pre-operative radio-chemotherapy compared to post-operative treatment in terms of minor acute and late toxicity, better local control and greater proportion of patients with preserved intestinal continuity. However, there are still many unresolved questions, such as the role of short-course pre-operative radiotherapy, the role of post-operative chemotherapy after neoadjuvant treatment, whether the type of surgery can be adjusted to the tumour's response to pre-operative treatment, and whether a more aggressive systemic treatment would improve the outcome of the disease so that we might be able to avoid radiotherapy. The paper describes the role of radiotherapy in the combined treatment of rectal cancer.

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