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Title:Slabost in bruhanje pri bolnikih na sistemskem zdravljenju raka
Authors:ID Borštnar, Simona (Author)
Files:.pdf PDF - Presentation file, download (106,54 KB)
MD5: F22DCFC6BDF27280AC7073037A0C2407
PID: 20.500.12556/dirros/dd7174a5-5e6f-4e5b-aa01-c69ef2428d99
 
Language:Slovenian
Typology:1.04 - Professional Article
Organization:Logo OI - Institute of Oncology
Abstract:Preprečevanje ter kontrola slabosti in bruhanja sta med najpomembnejšimi nalogami pri podpornem zdravljenju bolnikov z rakom. Poznamo akutno, pozno in anticipatorno slabost, ki so povzročene s citostatsko terapijo, ter kronično slabost in bruhanje pri bolnikih z napredovalim rakom. Osnova antiemetskega zdravljenja je nevrokemijska kontrola slabosti in bruhanja. V sluznici prebavil in v osrednjem živčevju so številni serotoninski, nevrokininski, dopaminski, histaminski in drugi receptorji, na katere se vežejo ustrezni prenašalci. Mnogi antiemetiki delujejo po mehanizmu kompetitivne inhibicije prek teh receptorjev tako v perifernem kot v osrednjem živčevju.
Publication status:Published
Publication version:Version of Record
Year of publishing:2009
Number of pages:str. 51-53
Numbering:Letn. 13, št. 1
PID:20.500.12556/DiRROS-8795 New window
UDC:616-006
ISSN on article:1408-1741
URN:URN:NBN:SI:doc-261AOQ4H
COBISS.SI-ID:25711321 New window
Copyright:by Authors
Note:BSDOCID145293;
Publication date in DiRROS:31.08.2018
Views:2627
Downloads:667
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Record is a part of a journal

Title:Onkologija. strokovni časopis za zdravnike
Shortened title:Onkologija
Publisher:Onkološki inštitut
ISSN:1408-1741
COBISS.SI-ID:65324032 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:31.08.2018

Secondary language

Language:English
Title:Systemic Treatment-Induced Vomiting and Nausea
Abstract:Prevention and control of nausea and vomiting are of paramount importance in the treatment of cancer patients. The most commonly described types are acute, delayed, and anticipatory chemotherapyinduced nausea and vomiting and chronic nausea and vomiting in advanced cancer patients. The basis for antiemetic therapy is the neurochemical control of both. Although the exact mechanism is not well understood,the peripheral neuroreceptors and the chemoreceptor trigger zone are known to contain receptors for serotonin, substance P, dopamine, histamine, opioids, and numerous other endogenous neurotransmitters. Many antiemetics act by competitively blocking the receptors for these substances, thereby inhibiting stimulation of peripheral nerves at the chemoreceptor zone, and perhaps at the vomiting center.


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