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Title:
Vloga in napredek zdravljenja pljučnega raka z zaviralci imunskih kontrolnih točk
Authors:
ID
Janžič, Urška
(
Author
)
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(333,85 KB)
MD5: D5A227C0BEBF17839B76C75DAD18F549
Language:
Slovenian
Typology:
1.02 - Review Article
Organization:
SFD - Slovenian Pharmaceutical Society
Abstract:
Zaviralci imunskih kontrolnih točk so bistveno spre menili zdravljenje pljučnega raka, ki je že historično bolezen z zelo slabo prognozo in preživetjem. Naj večji napredek je bil dosežen pri nedrobnoceličnem raku pljuč, kjer so zaviralci imunskih kontrolnih točk postali standard zdravljenja tako v prvi, kot tudi v drugi liniji. Pri drobnoceličnem raku pljuč so zaviralci imunskih kontrolnih točk prvič po desetletjih izboljšali celokupno preživetje. V prispevku so predstavljeni mehanizmi delovanja zaviralcev imunskih kontrolnih točk ter ključne klinične študije, ki so dokazale iz boljšanje celokupnega preživetja ob zdravljenju z njimi.
Publication status:
Published
Publication version:
Version of Record
Publication date:
01.05.2026
Year of publishing:
2026
Number of pages:
str. 139-145
Numbering:
Letn. 77, št. 2
PID:
20.500.12556/DiRROS-31044
UDC:
616.24-006:615.277
ISSN on article:
2536-4316
COBISS.SI-ID:
280073475
Note:
Nasl. z nasl. zaslona; Opis vira z dne 2. 6. 2026;
Publication date in DiRROS:
10.07.2026
Views:
100
Downloads:
40
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Record is a part of a journal
Title:
Farmacevtski vestnik : strokovno glasilo slovenske farmacije
Publisher:
Slovensko farmacevtsko društvo
ISSN:
2536-4316
COBISS.SI-ID:
288686336
Licences
License:
CC BY-NC 4.0, Creative Commons Attribution-NonCommercial 4.0 International
Link:
http://creativecommons.org/licenses/by-nc/4.0/
Description:
A creative commons license that bans commercial use, but the users don’t have to license their derivative works on the same terms.
Licensing start date:
01.01.2025
Secondary language
Language:
English
Title:
Role and advances of lung cancer treatment with immune checkpoint inhibitors
Abstract:
Immune checkpoint inhibitors have significantly transformed the treatment of lung cancer that has historically been a poor prognosis disease. The greatest progress has been achieved in non-small cell lung cancer, where immune checkpoint inhibi tors are now the standard treatment in first-line and second-line therapy. In small cell lung cancer, im mune checkpoint inhibitors have achieved the first meaningful survival improvement in decades. This article summarizes mechanisms of action and key clinical trials that have exhibited improved survival in lung cancer patients.
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