| Title: | Sarcopenic obesity in cancer |
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| Authors: | ID Jurdana, Mihaela (Author)
ID Čemažar, Maja (Author) |
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| Files: |  PDF - Presentation file, download (443,36 KB)
MD5: 5EB35325588DBC2282412D497AB54EB9
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| Language: | English |
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| Typology: | 1.02 - Review Article |
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| Organization: |  DRO - Association of Radiology and Oncology
 OI - Institute of Oncology
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| Abstract: | Sarcopenic obesity is a relatively new term. It is a clinical condition characterized by sarcopenia (loss of muscle mass and function) and obesity (increase in fat mass) that mainly affects older adults. As the incidence of sarcopenia and obesity increases worldwide, sarcopenic obesity is becoming a greater problem also in cancer patients. In fact, sarcopenic obesity is associated with poorer treatment outcomes, longer hospital stays, physical disability, and shorter survival in several cancers. Oxidative stress, lipotoxicity, and systemic inflammation, as well as altered expression of skeletal muscle anti-inflammatory myokines in sarcopenic obesity, are also associated with carcinogenesis. Conclusions. Reported prevalence of sarcopenic obesity in cancer varies because of heterogeneity in definitions and variability in diagnostic criteria used to estimate the prevalence of sarcopenia and obesity. Therefore, the aim of this review is to describe the definitions, prevalence, and diagnostic criteria as well as the mechanisms that cancer has in common with sarcopenic obesity. |
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| Keywords: | sarcopenia, obesity, cancer, inflammation |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 01.03.2024 |
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| Publisher: | Association of Radiology and Oncology |
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| Year of publishing: | 2024 |
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| Number of pages: | str. 1-8, I |
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| Numbering: | Vol. 58, no. 1 |
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| Source: | Ljubljana |
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| PID: | 20.500.12556/DiRROS-30412  |
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| UDC: | 616-006 |
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| ISSN on article: | 1318-2099 |
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| DOI: | 10.2478/raon-2024-0011 |
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| COBISS.SI-ID: | 186658051 |
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| Publication date in DiRROS: | 24.06.2026 |
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| Views: | 157 |
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| Downloads: | 72 |
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