| Title: | Treatment of foreign body granulomas with combined enzyme therapy |
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| Authors: | ID Castelanich, Desirée Giselle (Author)
ID Pascuzzi, Delfina (Author)
ID López Berroa, Jorge (Author) |
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| Files: |  URL - Source URL, visit https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2025.17/actaapa.2025.17.pdf
 PDF - Presentation file, download (21,13 MB)
MD5: 5796430F5713323B9CD22DEF5FF82764
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| Language: | English |
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| Typology: | 1.03 - Other scientific articles |
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| Organization: |  ZSD - Association of Slovenian Dermatovenereologists
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| Abstract: | Introduction: Granulomas are focal aggregates of inflammatory cells that form in response to a persistent inflammatory stimulus. Available therapies include surgical and nonsurgical management, and current evidence is based on case series or case reports. Methods: Two case reports of foreign body granulomas treated with a combination of recombinant enzymes (hyaluronidase, collagenase, and lipase of bacterial origin) are presented. Results: Following three sessions of combined enzyme treatment with a scheduled protocol, both patients showed clinical improvement without any reported adverse events. Conclusions: Combined enzyme therapy is an effective, safe, minimally invasive, innovative approach for the treatment of foreign body granulomas. |
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| Keywords: | granuloma, combined enzyme treatment, collagenase, hyaluronidase, lipase |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 26.12.2024 |
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| Article acceptance date: | 27.03.2025 |
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| Publication date: | 01.06.2025 |
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| Place of publishing: | Ljubljana |
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| Publisher: | Združenje slovenskih dermatovenerologov |
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| Year of publishing: | 2025 |
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| Number of pages: | str. 75-77 |
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| Numbering: | Vol. 34, issue 2 |
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| PID: | 20.500.12556/DiRROS-29893  |
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| UDC: | 616.5:579 |
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| ISSN on article: | 1318-4458 |
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| DOI: | 10.15570/actaapa.2025.17 |
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| COBISS.SI-ID: | 259281155 |
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| Publication date in DiRROS: | 09.06.2026 |
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| Views: | 77 |
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| Downloads: | 56 |
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