| Title: | Navigating intraductal papillary mucinous neoplasm management through fukuoka consensus vs. european evidence-based guidelines on pancreatic cystic neoplasms : a study on two European centers |
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| Authors: | ID Djordjević, Vladimir (Author) ID Knezevic, Djordje (Author) ID Trotovšek, Blaž (Author) ID Tomažič, Aleš (Author) ID Petrič, Miha (Author) ID Hadžialjević, Benjamin (Author) ID Grubor, Nikica (Author) ID Djokić, Mihajlo (Author) |
| Files: | PDF - Presentation file, download (450,80 KB) MD5: ABA8B4F0CBD2183BBB1A472D4E39C5CA
URL - Source URL, visit https://www.mdpi.com/2072-6694/16/11/2156
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | UKC LJ - Ljubljana University Medical Centre
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| Abstract: | This study addresses the critical need for the accurate diagnosis and management of intraductal papillary mucinous neoplasms (IPMNs), which are pancreatic cystic neoplasm types holding a substantial potential for malignancy. It evaluates the diagnostic effectiveness of the Fukuoka consensus guidelines and the European evidence-based guidelines in detecting high-grade dysplasia/invasive carcinoma in IPMNs, utilizing a retrospective analysis of 113 patients from two European medical centers. The methods include a comparative analysis of clinical, radiological, and endoscopic ultrasonography data, alongside an assessment of guideline-driven diagnostic performance. The results demonstrate that both guidelines offer similar accuracy in identifying severe disease stages in IPMNs, with certain clinical markers-such as jaundice, solid mass presence, and an increase in CA 19-9 levels-being pivotal in predicting the need for surgical intervention. This study concludes that while both guidelines provide valuable frameworks for IPMN management, there is an inherent need for further research to refine these protocols and improve patient-specific treatment strategies. This research contributes to the ongoing discourse on optimizing diagnostic and treatment paradigms for pancreatic cystic neoplasms, aiming to enhance clinical outcomes and patient care in this challenging medical field. |
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| Keywords: | IPMN, Serbia, Slovenia |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Year of publishing: | 2024 |
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| Number of pages: | str. 1-16 |
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| Numbering: | Vol. 16, no. 11 |
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| PID: | 20.500.12556/DiRROS-29755  |
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| UDC: | 61 |
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| ISSN on article: | 2072-6694 |
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| DOI: | 10.3390/cancers16112156  |
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| COBISS.SI-ID: | 201790211  |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 15. 7. 2024;
article no.2156;
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| Publication date in DiRROS: | 04.06.2026 |
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| Views: | 28 |
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| Downloads: | 12 |
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