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Title:The role of ultra-rapid-acting insulin analogs in diabetes : an expert consensus
Authors:ID Giorgino, Francesco (Author)
ID Battelino, Tadej (Author)
ID Bergenstal, Richard (Author)
ID Forst, Thomas (Author)
ID Green, Jennifer B. (Author)
ID Mathieu, Chantal (Author)
ID Rodbard, Helena W. (Author)
ID Schnell, Oliver (Author)
ID Wilmot, Emma G. (Author)
Files:.pdf PDF - Presentation file, download (166,87 KB)
MD5: E03DCD31E1C059A8376DA65488C1BE01
 
URL URL - Source URL, visit https://journals.sagepub.com/doi/epub/10.1177/19322968231204584
 
Language:English
Typology:1.02 - Review Article
Organization:Logo UKC LJ - Ljubljana University Medical Centre
Abstract:Ultra-rapid-acting insulin analogs (URAA) are a further development and refinement of rapid-acting insulin analogs. Because of their adapted formulation, URAA provide an even faster pharmacokinetics and thus an accelerated onset of insulin action than conventional rapid-acting insulin analogs, allowing for a more physiologic delivery of exogenously applied insulin. Clinical trials have confirmed the superiority of URAA in controlling postprandial glucose excursions, with a safety profile that is comparable to the rapid-acting insulins. Consequently, many individuals with diabetes mellitus may benefit from URAA in terms of prandial glycemic control. Unfortunately, there are only few available recommendations from authoritative sources for use of URAA in clinical practice. Therefore, this expert consensus report aims to define populations of people with diabetes mellitus for whom URAA may be beneficial and to provide health care professionals with concrete, practical recommendations on how best to use URAA in this context
Keywords:ultra-rapid-acting insulin, URLi, faster aspart, insulin therapy, type I diabetes, type 2 diabetes
Publication status:Published
Publication version:Version of Record
Year of publishing:2025
Number of pages:str. 452-469
Numbering:Vol. 19, iss. 2
PID:20.500.12556/DiRROS-29138 New window
UDC:616.379
ISSN on article:1932-3107
DOI:10.1177/19322968231204584 New window
COBISS.SI-ID:198982147 New window
Publication date in DiRROS:22.04.2026
Views:74
Downloads:52
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Record is a part of a journal

Title:Journal of diabetes science and technology
Publisher:Diabetes Technology Society
ISSN:1932-3107
COBISS.SI-ID:24028121 New window

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