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Title:Resuscitation in oncology : limits, ethics, practice, and humanity
Authors:ID Andjelkovič, Lea (Author)
ID Krnojelac, Milan (Author)
ID Potočnik, Iztok (Author)
Files:.pdf PDF - Presentation file, download (782,43 KB)
MD5: 2C77245F1B1A720B88279AEADFDC9510
 
URL URL - Source URL, visit https://www.mdpi.com/1718-7729/33/4/202
 
Language:English
Typology:1.02 - Review Article
Organization:Logo UKC LJ - Ljubljana University Medical Centre
Abstract:Introduction: Cardiopulmonary resuscitation (CPR) is one of the most consequential decisions in clinical medicine—a pivotal moment between life and death where science, ethics, and humanity intersect. Although advances in systems of care, technology, and training have refined technique and logistics, outcomes do not consistently result in meaningful, neurologically intact survival. In oncology—where disease trajectories are heterogeneous, treatment burdens substantial, and organ reserve often limited—these tensions are especially pronounced. Methods and approaches: This manuscript examines resuscitation as a medical, ethical, and human process, with explicit focus on patients with cancer. We review contemporary strategies for early recognition of deterioration (MEWS, NEWS, MET activation), team preparedness through Immediate Life Support (ILS), and structured decision-making at the boundaries of resuscitation. We also address communication with patients and families, the legal framework of Do-Not-Resuscitate (DNR) orders, and the distinctions among treatment forgoing, palliative sedation, and euthanasia, emphasising oncology-specific considerations such as metastatic burden, treatment intent (curative vs. palliative), performance status, and organ reserve. Results and discussion: The overall effectiveness of resuscitation remains modest (approximately 5–20% survival), highlighting the importance of prevention and early intervention. In cancer care, the limits of resuscitation are both clinical and ethical, requiring proportionality between the likely benefit and the risks of prolonging suffering, careful attention to prognosis and expected neurological outcomes, and rigorous alignment with goals of care. Early and ongoing involvement of palliative services, along with robust long-term care pathways, provides humane, value-concordant alternatives for patients with advanced disease. Psychotherapists and chaplains play integral roles in supporting families and clinical staff. Structured post-event debriefing and system-level safeguards are essential to mitigate burnout and moral distress within oncology teams. Initiating or discontinuing resuscitation in oncology requires expertise, empathy, and moral clarity. Dignity-preserving care depends on aligning interventions with patient values and realistic clinical endpoints. Acceptance of the natural course of dying represents an important component of responsible and patient-centred medical care.
Keywords:burnout, debriefing, palliative care, DNR, intensive care
Publication status:Published
Publication version:Version of Record
Year of publishing:2026
Number of pages:str. 1-17
Numbering:Vol. 33, issue 4, ǂarticle no. ǂ202
PID:20.500.12556/DiRROS-28827 New window
UDC:616.1
ISSN on article:1718-7729
DOI:10.3390/curroncol33040202 New window
COBISS.SI-ID:273953795 New window
Note:Nasl. z nasl. zaslona; Opis vira z dne 2. 4. 2026;
Publication date in DiRROS:08.04.2026
Views:40
Downloads:13
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Record is a part of a journal

Title:Current oncology
Publisher:Multimed
ISSN:1718-7729
COBISS.SI-ID:523618841 New window

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License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

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