| Title: | Variation in child serum cholesterol and prevalence of familiar hypercholesterolemia : the health oriented pedagogical project (HOPP) |
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| Authors: | ID Fabiani, Ester (Author), et al. |
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| Files: |  PDF - Presentation file, download (866,38 KB)
MD5: D0EC4F685E535F6BFFDCDCCB8257E8D6
 URL - Source URL, visit https://journals.sagepub.com/doi/epub/10.1177/2333794X221079558
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  UKC LJ - Ljubljana University Medical Centre
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| Abstract: | Early stages of atherosclerosis may develop in childhood due to hyperlipidemia. The aims are to investigate the prevalence of familiar hypercholesterolemia in 6 to 12-year-old children and to study the deviation in cholesterol measures. Anthropometric data and venous blood were collected from children participating in the Health Oriented Pedagogical Project (HOPP). Out of 18 children with TC > 6.0 mmol/L, 15 were tested genetically and none diagnosed with FH. The prevalence of TC > 6.0 mmol/L declined from 1.3% in 2015 to 0.5% in 2016. The mean TC was 4.30 mmol/L both years, which is lower than in earlier studies. Usage of a single TC measurement and a threshold of TC > 6.0 mmol/L in screening children for FH, may not be a good screening strategy. While lipid values have a good reliability across 2 measurements, there are variations in individual TC levels across 1 year. |
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| Keywords: | children, cholesterol, familiar hypercholesterolemia, hyperlipidemia, prevalence |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Year of publishing: | 2022 |
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| Number of pages: | str. 1-8 |
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| Numbering: | Vol. 9 |
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| PID: | 20.500.12556/DiRROS-28625  |
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| UDC: | 616.153.922 |
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| ISSN on article: | 2333-794X |
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| DOI: | 10.1177/2333794X221079558 |
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| COBISS.SI-ID: | 224287235 |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 28. 1. 2025;
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| Publication date in DiRROS: | 26.03.2026 |
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| Views: | 130 |
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| Downloads: | 97 |
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| Metadata: |    |
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