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Title:Effect of rearing systems and dietary protein levels on the skeletal muscle histomorphology and transcriptome profiles in indigenous Krškopolje Pig : expression profiling by high throughput sequencing
Authors:ID Vrecl, Milka (Author)
ID Škrlep, Martin (Author)
ID Poklukar Žnidaršič, Klavdija (Author)
ID Fazarinc, Gregor (Author)
ID Štrbenc, Malan (Author)
ID Čandek-Potokar, Marjeta (Author)
Files:URL URL - Source URL, visit https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE320088
Description: Podatki nedostopni, 20. 3. 2026, dostopni po 20. 2. 2030
 
.pdf PDF - Presentation file. (726,02 KB, This file will be accessible after 20.02.2030)
MD5: 969957605D665B3927658E5566FBD90F
 
Language:English
Typology:2.20 - Complete scientific database of research data
Organization:Logo KIS - Agricultural Institute of Slovenia
Abstract:RNA-sequencing was performed to compare the effects of production systems (conventional indoor, vs. outdoor) and diets (standard protein, HP, vs. low protein, LP) within each rearing system on the transcriptomic profiles of two skeletal muscles, longissimus thoracis et lumborum (LL) and semispinalis capitis (SSC). Differentially expressed genes (DEGs) were identified with |log2FC| > 1 and q-value < 0.005. The effect of rearing system (indoor vs. outdoor) resulted in 354 DEGs in LL and 334 DEGs in SSC. The effect of diet within individual rearing system was less pronounced. In LL, HP vs. LP resulted in 23 DEGs under indoor and none under outdoor rearing system. In SSC, HP vs. LP resulted in 28 DEGs under indoor and 30 DEGs under outdoor rearing system. Pathway enrichment analysis revealed 42 pathways significantly enriched for HP vs. LP in the outdoor rearing system (across both muscles); additionally, 11 pathways were altered specifically in SSC for HP vs. LP under indoor rearing system, and 27 pathways were altered specifically in LL for HP vs. LP under outdoor rearing system
Keywords:RNA sequences, pigs, adipose tissue, high throughput sequencing, RNA, transcriptome profiles, gene expression, locel breeds, hybrid breeds, data, data set
Publication status:Published
Publication version:Version of Record
Publication date:20.02.2026
Place of publishing:Bethesda
Place of performance:Bethesda
Publisher:Gene Expression Omnibus (GEO)
Year of publishing:2026
Year of performance:2026
Number of pages:1 spletni vir
PID:20.500.12556/DiRROS-28453 New window
UDC:636
COBISS.SI-ID:272369923 New window
Note:Nasl. z. nasl. zaslona; Opis vira z dne 20. 3. 2026;
Publication date in DiRROS:20.03.2026
Views:244
Downloads:47
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Document is financed by a project

Funder:EC - European Commission
Project number:101000236
Name:GEroNIMO: Genome and Epigenome eNabled breedIng in MOnogastrics
Acronym:GEroNIMO

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:J4-3094-2021
Name:Identifikacija genetskih in metabolnih lastnosti mastnih pasem prašičev - primer krškopoljskega prašiča

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P4-0053-2019
Name:Endokrini, imunski in encimski odzivi pri zdravih in bolnih živalih

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P4-0133-2018
Name:Trajnostno kmetijstvo

Secondary language

Language:Slovenian
Keywords:RNK sekvence, prašiči, režim prehranjevanja, nivo proteinov v krmi, histomorfološke lastnosti, skeletno mišičan muskulatura, visokozmogljivo sekvenciranje, RNK, profili transkriptomoov, izražanje genov, lokalne pasme, sodobne pasme, vsebnost beljakovin v prehrani, podatki, podatkovni set, Sus scrofa


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