| Title: | Vascular access for hemodialysis and catheter-related bloodstream infections : a survey on preventive measures and treatment strategies by the EPDWG and ESPN Dialysis Working Group |
|---|
| Authors: | ID Bakkaloglu, Sevcan A. (Author)
ID Leventoğlu, Emre (Author)
ID Ezgü, Defne (Author)
ID Bayrakçı, Umut Selda (Author)
ID Buder, Kathrin (Author)
ID Canpolat, Nur (Author)
ID Rus, Rina (Author), et al. |
|---|
| Files: |  PDF - Presentation file, download (840,08 KB)
MD5: DBD1DA19A0B9CAD8B417F9495A88BF8D
 URL - Source URL, visit https://link.springer.com/article/10.1007/s00431-025-06703-7
|
|---|
| Language: | English |
|---|
| Typology: | 1.01 - Original Scientific Article |
|---|
| Organization: |  UKC LJ - Ljubljana University Medical Centre
|
|---|
| Abstract: | The choice of vascular access (VA) plays a key role in the success of hemodialysis (HD). Despite their widespread use, central venous catheters (CVCs) are associated with higher rates of dysfunction, thrombosis, and catheter-related bloodstream infections (CRBSI). We investigated current practices in pediatric HD across European pediatric nephrology centers, focusing on VA choices, infection control measures, and CRBSI management. An online questionnaire was e-mailed to 119 members of the European Society for Pediatric Nephrology (ESPN) Dialysis Working Group and European Pediatric Dialysis Working Group (EPDWG). Descriptive statistics were used to summarize practices across centers, comparative analyses between centers in countries with Human Development Index (HDI) > 0.90 and < 0.90. Thirty-one centers across Europe participated in the survey. CVCs were the primary VA in 73.1% of the centers. Twenty (66.7%) centers reported malfunction as the most common CVC complication, followed by catheter thrombosis (19.4%) and CRBSI (12.9%). The diagnostic approach for CRBSI varied widely, with 35.4% of centers relying on a single positive catheter culture, while 57.9% did not collect a second culture from the peripheral vein or HD circuit. The most common empirical treatment was glycopeptides combined with third-generation cephalosporins. Nearly all centers used intravenous antibiotics for less than 3 weeks, and over half modified lock solutions with antibiotics following CRBSI diagnosis. Catheter removal practices were inconsistent, even in cases of severe infection. Centers reported a total of 548 HD patients. Exit-site infections and CRBSI were observed in 98 (17.8%) and 155 (28.2%) patients, respectively. CRBSI rates and CRBSI-related catheter replacements were significantly higher in centers from countries with HDI < 0.90 and in centers without a dedicated pediatric HD unit. Conclusion: The suboptimal adherence to current VA recommendations and wide variability in catheter care practices including the prevention, diagnosis, and management of CRBSI highlight the need for standardized pediatric-specific protocols to enhance catheter longevity and improve patient outcomes. |
|---|
| Keywords: | vascular access, hemodyalysis, treatment, children |
|---|
| Publication status: | Published |
|---|
| Publication version: | Version of Record |
|---|
| Year of publishing: | 2026 |
|---|
| Number of pages: | str. 1-11 |
|---|
| Numbering: | Vol. 185, issue 1 |
|---|
| PID: | 20.500.12556/DiRROS-28319  |
|---|
| UDC: | 616-053.2 |
|---|
| ISSN on article: | 1432-1076 |
|---|
| DOI: | 10.1007/s00431-025-06703-7 |
|---|
| COBISS.SI-ID: | 267816451 |
|---|
| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 9. 2. 2026;
|
|---|
| Publication date in DiRROS: | 13.03.2026 |
|---|
| Views: | 46 |
|---|
| Downloads: | 30 |
|---|
| Metadata: |    |
|---|
|
:
|
Copy citation |
|---|
| | | | Share: |  |
|---|
Hover the mouse pointer over a document title to show the abstract or click
on the title to get all document metadata. |
