| Title: | Contrast-enhanced ultrasound (CEUS) and ultra-microangiography (UMA) in critically ill children with acute kidney injury |
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| Authors: | ID Ogorevc, Nace (Author) ID Slak, Peter (Author) ID Nikšić, Stevan (Author) ID Novljan, Gregor (Author) ID Fister, Petja (Author) ID Plut, Domen (Author) |
| Files: | PDF - Presentation file, download (2,87 MB) MD5: 0757EA5FA5C8C340148C6B341BA2A20D
URL - Source URL, visit https://www.mdpi.com/2227-9067/11/10/1205/pdf?version=1727691044
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| Language: | English |
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| Typology: | 1.02 - Review Article |
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| Organization: | UKC LJ - Ljubljana University Medical Centre
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| Abstract: | Acute kidney injury (AKI) is an acute condition of impaired kidney function with decreased glomerular filtration rate, which results in dysregulation in volume, electrolyte, and acid–base equilibrium. AKI can be a life-threatening condition and can also lead to chronic kidney disease. It is important to diagnose AKI early in the course of the disease or to predict its development, as this can influence therapeutic decisions, outcome, and, consequently, the prognosis. In clinical practice, an elevated serum creatinine concentration remains the most common laboratory indicator for diagnosing AKI. However, due to the delay in its rise, creatinine levels are often insensitive and inaccurate for early diagnosis. Novel biomarkers of kidney tubular injury and the renal angina index have shown promise in predicting AKI earlier and more accurately. Contrast-enhanced ultrasonography (CEUS) and ultra-microangiography (UMA) are radiological methods that can quantify renal microperfusion and may be able to predict the development of AKI. They have not yet been used for quantifying renal perfusion in children with risk factors for developing AKI. Further research is needed to compare these sonographic techniques with the renal angina index and emerging kidney injury biomarkers for predicting acute kidney injury (AKI) in both children and adults |
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| Keywords: | acute kidney injury, contrast-enhanced ultrasound, ultra-microangiography |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Year of publishing: | 2024 |
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| Number of pages: | str. 1-11 |
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| Numbering: | Vol. 11, iss. 10, ǂ[article no.] ǂ1205 |
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| PID: | 20.500.12556/DiRROS-27874  |
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| UDC: | 616-053.2 |
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| ISSN on article: | 2227-9067 |
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| DOI: | 10.3390/children11101205  |
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| COBISS.SI-ID: | 230016003  |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 24. 3. 2025;
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| Publication date in DiRROS: | 26.02.2026 |
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| Views: | 162 |
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| Downloads: | 63 |
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