| Title: | Influences on and prevention of self-harm behavior among the most at-risk adolescents : study protocol for the SH-MARA prospective longitudinal cohort study |
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| Authors: | ID Sernec Podnar, Lana (Author)
ID Tomažič, Petra (Author)
ID Tomašević Kramer, Anja (Author)
ID Plemeniti Tololeski, Barbara (Author)
ID Tasevski, Gorjan (Author)
ID Rosenstein, Žiga (Author)
ID Klemenčič, Simona (Author)
ID Battelino, Tadej (Author)
ID Vrhovšek, Blaž (Author)
ID Lahovnik, Tadej (Author)
ID Kovač, Jernej (Author)
ID Sharp, Carla (Author)
ID Jenko Bizjan, Barbara (Author)
ID Karakatič, Sašo (Author)
ID Drobnič Radobuljac, Maja (Author) |
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| Files: |  PDF - Presentation file, download (1,09 MB)
MD5: D89DA9E7E6ECDFF51F0C3539C249D44A
 URL - Source URL, visit https://dk.um.si/IzpisGradiva.php?id=95735
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  UKC LJ - Ljubljana University Medical Centre
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| Abstract: | Background Both suicidal and non-suicidal self-injuring behaviors (NSSI) are common during adolescence In Slovenia, adolescent suicide rates are high, making suicide the leading cause of death in the year 2022 in this age group. These behaviors are influenced by a complex interplay of environmental, psychological, and genetic factors. Previous research has identified risk and protective factors mainly for suicidal behavior in adults, a notable gap in understanding these factors in adolescents remains, especially for NSSI. Notably there is an important lack of effective clinical tools or psychometric assessment methods to reliably assess the risk for either suicidal or NSSI behaviors in acutely hospitalized adolescents. Methods and analysis The proposed study uses a mixed-method observational design consisting of a prospective longitudinal cohort component involving adolescents hospitalized for high risk of DSH, and a cross-sectional comparison with a control group of healthy adolescents recruited from primary care settings. It is aimed at identifying genetic, psychosocial, and clinical factors associated with suicidal behaviors and NSSI in adolescents. The study group is recruited from adolescents aged 12–19, admitted to the Intensive Child and Adolescent Psychiatry Unit in Ljubljana due to severe self-harm risk. Exclusion criteria include involuntary treatment, acute psychotic disorders, intellectual disability, severe physical or central nervous system illnesses and acute intoxication. The control group comprises adolescents of comparable age, recruited through regular scheduled health check-ups in Slovenia. Exclusion criteria include suicidality, severe mental disorder, a history of self-harm behavior in a first-degree relative, intellectual disability, severe physical or central nervous system illnesses and acute intoxication. Enrollment runs from February 1, 2023, to December 31, 2025. Participation is voluntary, requiring parental or guardian consent for those 14 or younger |
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| Keywords: | adolescents, deliberate self-harm, non-suicidal self-injury, suicidal behavior, intensive psychiatry, personality disorder, traumatic experience, genetics, epigenetics |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Year of publishing: | 2025 |
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| Number of pages: | 8 str. |
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| Numbering: | Vol. 25, [article no.] 943 |
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| PID: | 20.500.12556/DiRROS-27774  |
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| UDC: | 615.89 |
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| ISSN on article: | 1471-244X |
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| DOI: | 10.1186/s12888-025-07298-x |
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| COBISS.SI-ID: | 253567491 |
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| Note: | Nasl. z nasl. zaslona;
Soavtorji: Petra Tomažič, Anja Tomašević Kramer, Barbara Plemeniti Tololeski, Gorjan Tasevski, Žiga Rosenstein, Simona Klemenčič, Tadej Battelino, Blaž Vrhovšek, Tadej Lahovnik, Jernej Kovač, Carla Sharp, Barbara Jenko Bizjan, Sašo Karakatič & Maja Drobnič Radobuljac;
Opis vira z dne 17. 10. 2025;
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| Publication date in DiRROS: | 24.02.2026 |
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| Views: | 41 |
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| Downloads: | 18 |
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