| Title: | Impact of spaceflight on endocrine, metabolic and kidney function: : current evidence, open issues, and potential countermeasures |
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| Authors: | ID Magni, Paolo (Author)
ID Ricci, Giulia (Author)
ID Narici, Marco Vincenzo (Author)
ID Ferranti, Francesca (Author) |
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| Files: |  PDF - Presentation file, download (1,13 MB)
MD5: 98C4A0AF58523538FA34F762BA91ABBB
 URL - Source URL, visit https://pmc.ncbi.nlm.nih.gov/articles/PMC12752379/
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| Language: | English |
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| Typology: | 1.02 - Review Article |
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| Organization: |  ZRS Koper - Science and Research Centre Koper
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| Abstract: | Changes in endocrine and kidney functions have been associated with spaceflight. Here, we discuss the most relevant evidence about the impact of spaceflight on the cardiometabolic system, the cardiorenal function and the reproductive/gonadal axis. Notably, these changes appear to be interrelated with other organ/system functions, suggesting the need of a systemic approach leading to a more comprehensive understanding of physiological and health-related impacts of the space environment. Therefore, this review will also focus on the need to move space endocrinological research to multi-omics approaches and the implementation of “machine learning” and “data mining” strategies. |
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| Keywords: | cardiorenal function, metabolic changes, microgravity, oxidative stress, reproduction, space exposome., a |
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| Publication version: | Version of Record |
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| Article acceptance date: | 13.11.2025 |
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| Publication date: | 29.12.2025 |
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| Year of publishing: | 2025 |
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| Number of pages: | str. 1-8 |
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| Numbering: | Vol. 23, art. 365 |
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| PID: | 20.500.12556/DiRROS-25151  |
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| UDC: | 611.61:612 |
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| ISSN on article: | 1741-7007 |
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| DOI: | 10.1186/s12915-025-02471-w |
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| COBISS.SI-ID: | 264401667 |
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| Copyright: | © The Author(s) |
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| Note: | Nasl. z nasl. zaslona;
Soavtorji: Giulia Ricci, Marco Narici, Francesca Ferranti;
Opis vira z dne 12. 1. 2026;
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| Publication date in DiRROS: | 12.01.2026 |
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| Views: | 47 |
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| Downloads: | 13 |
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| Metadata: |    |
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