| Title: | Association of preoperative smoking with the occurrence of postoperative pulmonary complications : a post hoc analysis of an observational study in 29 countries |
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| Authors: | ID Dorland, Galina (Author)
ID Saadat, W. (Author)
ID Meenen, David M.P. van (Author)
ID Serpa Neto, Ary (Author)
ID Hiesmayr, Michael (Author)
ID Novak, Barbka (Research coworker)
ID Pekle-Golež, Ana (Research coworker)
ID Jovanović, Miroljub (Research coworker)
ID Stražišar, Branka (Research coworker)
ID Markovič Božič, Jasmina (Research coworker)
ID Novak-Jankovič, Vesna (Research coworker)
ID Voje, Minca (Research coworker)
ID Grynyuk, Andriy (Research coworker)
ID Kostadinov, Ivan (Research coworker)
ID Spindler-Vesel, Alenka (Research coworker), et al. |
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| Files: |  PDF - Presentation file, download (1,45 MB)
MD5: 158808A9AFFC6BA152FEFE039F941916
 URL - Source URL, visit https://www.sciencedirect.com/science/article/pii/S0952818025001163
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  UKC LJ - Ljubljana University Medical Centre
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| Abstract: | Introduction: While smoking has been consistently identified as a significant contributor to postoperative complications, the existing literature on its association with postoperative pulmonary complications remains conflicting. Aim: We examined the association of preoperative smoking with the occurrence of postoperative pulmonary complications (PPCs). Methods: Post hoc analysis of an observational study in 146 hospitals across 29 countries. We included patients at increased risk of PPCs, according to the Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) score (≥ 26 points). The primary endpoint was the occurrence of one or more predefined PPCs in the first five postoperative days, including unplanned postoperative need for supplementary oxygen, respiratory failure, unplanned need for invasive ventilation, ARDS, pneumonia and pneumothorax. Secondary endpoints included length of hospital stay and in–hospital mortality. We performed propensity score matching to correct for factors with a known association with postoperative outcomes. Results: Out of 2632 patients, 531 (20.2 %) patients were smokers and 2102 (79.8 %) non-smokers. At five days after surgery, 101 (19.0 %) smokers versus 404 (19.2) non–smokers had developed one or more PPCs (P = 0.95). Respiratory failure was more common in smokers (5.1 %) than non–smokers (3.0 %) (P = 0.02), while rates of other PPCs like need for supplementary oxygen, invasive ventilation, ARDS, pneumonia, or pneumothorax did not differ between the groups. Length of hospital stay and mortality was not different between groups. Propensity score matching did not change the findings. Conclusion: The occurrence of PPCs in smokers is not different from non–smokers. |
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| Keywords: | anaesthesia, intraoperative ventilation, smoking, postoperative outcome, postoperative pulmonary complications, PPCs, respiratory complications |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Year of publishing: | 2025 |
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| Number of pages: | str. 1-10 |
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| Numbering: | Vol. 104, [article no.] 111856 |
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| PID: | 20.500.12556/DiRROS-24877  |
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| UDC: | 617 |
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| ISSN on article: | 1873-4529 |
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| DOI: | 10.1016/j.jclinane.2025.111856 |
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| COBISS.SI-ID: | 249939459 |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 23. 9. 2025;
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| Publication date in DiRROS: | 23.12.2025 |
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| Views: | 15 |
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| Downloads: | 7 |
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