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Title:Structural basis of bis-quinolinium ligands binding to quadruplex–duplex hybrids from PIM1 oncogene
Authors:ID Ghosh, Anirban (Author)
ID Harnos, Jakub (Author)
ID Stadlbauer, Petr (Author)
ID Šponer, Jiří (Author)
ID Lenarčič Živković, Martina (Author)
ID Trantírek, Lukáš (Author)
Files:URL URL - Source URL, visit https://academic.oup.com/nar/article/53/17/gkaf894/8251892
 
.pdf PDF - Presentation file, download (2,30 MB)
MD5: 60DA70A78728BFF410E400055BBA14A1
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo KI - National Institute of Chemistry
Publication status:Published
Publication version:Version of Record
Publication date:26.08.2025
Year of publishing:2025
Number of pages:str. 1-17
Numbering:Vol. 53, iss. 17, [article no.] gkaf894
PID:20.500.12556/DiRROS-23626 New window
UDC:577
ISSN on article:1362-4962
DOI:10.1093/nar/gkaf894 New window
COBISS.SI-ID:248937987 New window
Copyright:© The Author(s) 2025. Published by Oxford University Press.
Note:Nasl. z nasl. zaslona; Opis vira z dne 15. 9. 2025;
Publication date in DiRROS:15.09.2025
Views:319
Downloads:137
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Record is a part of a journal

Title:Nucleic acids research online
Shortened title:Nucleic acids res. online
Publisher:Oxford University Press
ISSN:1362-4962
COBISS.SI-ID:2172954 New window

Document is financed by a project

Funder:CERIC-ERIC
Project number:20217158
Name:NMR-based high-resolution structural characterization of ligand interactions with DNA G-quadruplex from PIM1 gene

Funder:Ministry of Education, Youth and Sports of the Czech Republic
Project number:LM2023042
Name:Czech Infrastructure for Integrative Structural Biology

Funder:Ministry of Education, Youth and Sports of the Czech Republic
Project number:CZ.02.01.01/00/23_015/0008175
Name:Innovation of Czech Infrastructure for Integrative Structural Biology

Funder:Ministry of Education, Youth and Sports of the Czech Republic
Project number:90254
Name:e-INFRA CZ

Funder:Ministry of Education, Youth and Sports of the Czech Republic
Project number:CZ.02.1.01/0.0/0.0/15_003/0000477
Name:Structural gymnastics of nucleic acids: from molecular principles through biological functions to therapeutic targets. Support of integrated research team
Acronym:SYMBIT

Funder:EC - European Commission
Funding programme:HE
Project number:101068280
Name:In vitro and In-cell characterization of Quadruplex-duplex hybrids: conformation, folding, and recognition by drug-like ligand molecule
Acronym:QDHassay

Funder:Grant Agency of Masaryk University
Project number:MUNI/JS/1849/2024
Name:Unraveling G-Quadruplex and Helicase-derived peptide interaction by spectroscopic and spectrometric methods

Funder:Grant Agency of Masaryk University
Project number:MUNI/J/0004/2021
Name:Role of the Planar Cell Polarity and Mitochondria Crosstalk in Fuelling Cell Migration

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P1-0242
Name:Kemija in struktura bioloških učinkovin

Funder:EC - European Commission
Funding programme:HE
Project number:101094131
Name:From fragments to high affinity binders interfacing integrated structural biology, medicinal chemistry and artificial intelligence
Acronym:Fragment-Screen

Funder:Czech Science Foundation
Project number:GF24-10605K
Name:Dynamic polymorphism of non-canonical nucleic acids structures in the intracellular space

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.

Secondary language

Language:Slovenian
Keywords:biokemija, g-kvadrupleksi, ligandi, NMR, DNK


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