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Title:Advanced delivery systems for gene editing : a comprehensive review from the GenE-HumDi COST action working group
Authors:ID Cavazza, Alessia (Author)
ID Molina-Estévez, Francisco J. (Author)
ID Plaza Reyes, ‪Álvaro (Author)
ID Ronco, Victor (Author)
ID Naseem, Asma (Author)
ID Malenšek, Špela (Author)
ID Pečan, Peter (Author)
ID Santini, Annalisa (Author)
ID Heredia, Paula (Author)
ID Aguilar-González, Araceli (Author)
ID Lainšček, Duško (Author)
Files:URL URL - Source URL, visit https://www.sciencedirect.com/science/article/pii/S2162253125000113
 
.pdf PDF - Presentation file, download (4,29 MB)
MD5: 4DDEDA2F28C282B36D69B2A0FD724800
 
Language:English
Typology:1.02 - Review Article
Organization:Logo KI - National Institute of Chemistry
Keywords:delivery strategies, European cooperation in science and technology, COST, GenE-HumDi, genome editing, base editors, delivery systems, regulatory guidelines
Publication status:Published
Publication version:Version of Record
Publication date:11.03.2025
Year of publishing:2025
Number of pages:str. 1-32
Numbering:Vol. 36, iss. 1, [article no.] 102457
PID:20.500.12556/DiRROS-23435 New window
UDC:602.6/.7
ISSN on article:2162-2531
DOI:10.1016/j.omtn.2025.102457 New window
COBISS.SI-ID:226357251 New window
Copyright:© 2025 The Author(s). Published by Elsevier Inc. on behalf of The American Society of Gene and Cell Therapy.
Note:Nasl. z nasl. zaslona; Opis vira z dne 17. 2. 2025;
Publication date in DiRROS:29.08.2025
Views:393
Downloads:167
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Record is a part of a journal

Title:Molecular therapy : Nucleic acids
Shortened title:Mol. ther., Nucleic acids
Publisher:Nature Pub. Group
ISSN:2162-2531
COBISS.SI-ID:1898619 New window

Document is financed by a project

Funder:COST - European Cooperation in Science and Technology
Project number:CA21113
Name:Genome Editing to Treat Humans Diseases (GenE-Humdi)

Funder:Fundación Pública Andaluza Progreso y Salud
Funding programme:Plan Andaluz de Investigación, Desarrollo e Innovación (PAIDI) 2020
Project number:ProyExcel_00875
Name:PRECLINICAL DEVELOPMENT OF A NEW TREATMENT FOR RELAPSED OR REFRACTORY ACUTE MYELOBLASTIC LEUKEMIA (R/R AML) COMBINING ALLOGENEIC ANTI CLL-1 CAR-T CELLS WITH IMMUNOSUPPRESSIVE EXOSOSOMES. (CARAML-EXO)

Funder:Instituto de Salud Carlos III
Funding programme:Recovery, Transformation and Resilience Plan - EU Next Generation Funds
Project number:RD21/0017/004

Funder:IKERBASQUE - Basque Foundation for Science
Name:Multidisciplinary approach for the study of CNS proteinopathies (synuclein and TDP-43) due to Basque ancestral mutations in LRRK2 (R1441G) and progranulin genes linked to familial Parkinson and frontotemporal dementia/als complexes
Acronym:NEURODEGENPROT

Funder:Spanish Ministry of Science and Innovation
Project number:RYC2018-024397-I
Name:CRISPR-Cas13 delivered antisense RNA molecules for research and therapeutics of splicing-related disorders

Funder:IKERBASQUE - Basque Foundation for Science
Project number:RF/2019/001

Funder:Ministry of Science Technological Development and Innovation of the Republic of Serbia
Project number:451-03-66/2024-03/200007

Funder:Ministerio de Ciencia, Innovación y Universidades
Project number:FPU22/03244

Funder:EC - European Commission
Funding programme:H2020
Project number:865797
Name:Development of Innovative Therapeutic Strategies for beta-hemoglobinopathies
Acronym:DITSB

Funder:Other - Other funder or multiple funders
Project number:PI22/01382
Name:Cerrando la brecha terapeutica para Distrofias Musculares Congenitas. Estrategias para mejorar la eficacia, liberacion y seguridad de terapias basadas en CRISPR/Cas9 y oligonucleotidos

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:J4-4563
Name:Uporaba izboljšanega sistema CRISPR/Cas za nevirusno produkcijo celic CAR-T

Funder:Novo Nordisk Foundation
Project number:NNF21OC0072031

Funder:Novo Nordisk Foundation
Project number:NNF21OC0068988

Funder:Lundbeck Foundation
Project number:R396-2022-350

Funder:M-ERA.Net and Innovation Fund Denmark
Project number:9355 PIECRISCI

Funder:EC - European Commission
Funding programme:HE
Project number:101165643
Name:Reducing Non-Human Primates in Non-Clinical Safety Assessment: The European Initiative on Minipig and Micropig Models
Acronym:NHPig

Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:16.01.2025
Applies to:Text and Data Mining valid from 2025-03-01 Text and Data Mining valid from 2025-03-01 Version of Record valid from 2025-01-16

Secondary language

Language:Slovenian
Keywords:biotehnologija, gensko urejanje, napredni dostavni sistemi, CRISPR


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