| Title: | Cold-induced anaphylaxis : new insights into clinical and genetic characteristics |
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| Authors: | ID Bizjak-Šuran, Mojca (Author)
ID Korošec, Peter (Author)
ID Košnik, Mitja (Author)
ID Šelb, Julij (Author)
ID Bidovec, Urška (Author)
ID Svetina, Manca (Author)
ID Zver, Samo (Author)
ID Dinevski, Dejan (Author)
ID Rijavec, Matija (Author) |
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| Files: |  PDF - Presentation file, download (1,97 MB)
MD5: 72BFE2B00525BBD32A80350B4BC2FFE4
 URL - Source URL, visit https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1558284/full
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
 UKC LJ - Ljubljana University Medical Centre
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| Abstract: | The pathogenesis of cold urticaria (ColdU) and cold-induced anaphylaxis (ColdA) remains poorly understood, and ColdA is underrepresented in anaphylaxis literature. Laboratory features to guide management are largely unknown. This study evaluated basal serum tryptase (BST) and total immunoglobulin E (IgE) levels in ColdU and ColdA, their associations with clinical features, and the utility of testing for the KIT p.D816V variant in blood leukocytes and hereditary a-tryptasemia (HaT). |
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| Keywords: | anaphylaxis, cold urticaria, hereditary α-tryptasemia, KIT p.D816V, mast cell, total IgE, tryptase |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 10.01.2025 |
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| Article acceptance date: | 11.02.2025 |
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| Publication date: | 01.01.2025 |
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| Publisher: | Frontiers Research Foundation, 2010- |
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| Year of publishing: | 2025 |
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| Number of pages: | str. [1-11] |
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| Numbering: | Vol. 16 |
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| Source: | Frontiers in immunology |
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| PID: | 20.500.12556/DiRROS-22491  |
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| UDC: | 616-097 |
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| ISSN on article: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1558284 |
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| COBISS.SI-ID: | 229318403 |
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| Copyright: | © 2025 Bizjak, Korošec, Košnik, Šelb, Bidovec-Stojkovič, Svetina, Zver, Dinevski and Rijavec. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are
credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 18. 3. 2025; |
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| Publication date in DiRROS: | 21.05.2025 |
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| Views: | 1078 |
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| Downloads: | 569 |
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