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Title:Cold-induced anaphylaxis : new insights into clinical and genetic characteristics
Authors:ID Bizjak, Mojca, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Korošec, Peter, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Košnik, Mitja, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Šelb, Julij, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Bidovec, Urška, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Svetina, Manca, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Zver, Samo (Author)
ID Dinevski, Dejan, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
ID Rijavec, Matija, Univerzitetna klinika za pljučne bolezni in alergijo Golnik (Author)
Files:URL URL - Source URL, visit https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1558284/full
 
.pdf PDF - Presentation file, download (1,97 MB)
MD5: 72BFE2B00525BBD32A80350B4BC2FFE4
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:The pathogenesis of cold urticaria (ColdU) and cold-induced anaphylaxis (ColdA) remains poorly understood, and ColdA is underrepresented in anaphylaxis literature. Laboratory features to guide management are largely unknown. This study evaluated basal serum tryptase (BST) and total immunoglobulin E (IgE) levels in ColdU and ColdA, their associations with clinical features, and the utility of testing for the KIT p.D816V variant in blood leukocytes and hereditary a-tryptasemia (HaT).
Keywords:anaphylaxis, cold urticaria, hereditary α-tryptasemia, KIT p.D816V, mast cell, total IgE, tryptase
Publication status:Published
Publication version:Version of Record
Submitted for review:10.01.2025
Article acceptance date:11.02.2025
Publication date:21.02.2025
Publisher:Frontiers Research Foundation, 2010-
Year of publishing:2025
Number of pages:str. [1-11]
Numbering:Vol. 16
Source:Frontiers in immunology
PID:20.500.12556/DiRROS-22491 New window
UDC:616-097
ISSN on article:1664-3224
DOI:10.3389/fimmu.2025.1558284 New window
COBISS.SI-ID:229318403 New window
Copyright:© 2025 Bizjak, Korošec, Košnik, Šelb, Bidovec-Stojkovič, Svetina, Zver, Dinevski and Rijavec. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Note:Nasl. z nasl. zaslona; Opis vira z dne 18. 3. 2025;
Publication date in DiRROS:21.05.2025
Views:616
Downloads:290
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Record is a part of a journal

Title:Frontiers in immunology
Shortened title:Front. immunol.
Publisher:Frontiers Research Foundation
ISSN:1664-3224
COBISS.SI-ID:30774233 New window

Document is financed by a project

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P3-0360
Name:Celostna obravnava alergijskih bolezni in astme v Sloveniji: od epidemiologije do genetike

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:21.02.2025
Applies to:Version of Record valid from 2025-02-21

Secondary language

Language:Slovenian
Keywords:anafilaksija, urtikarija zaradi mraza, dedna α-triptazemija, KIT p.D816V, mastociti, skupni IgE, triptaza


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