| Title: | Exposure to specific fungal lectins during adhesionimpairs biofilm formation of Listeria on polystyrene |
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| Authors: | ID Janež, Nikolaja, Institut "Jožef Stefan" (Author)
ID Ladányi, Márta (Author)
ID Sterniša, Meta (Author)
ID Jug, Blaž (Author)
ID Zupan, Tanja (Author)
ID Peternel, Tjaša (Author)
ID Sebastijanović, Aleksandar, Institut "Jožef Stefan" (Author)
ID Perišić, Milica, Institut "Jožef Stefan" (Author)
ID Karničar, Katarina, Institut "Jožef Stefan" (Author)
ID Taler-Verčič, Ajda, Institut "Jožef Stefan" (Author)
ID Turk, Dušan, Institut "Jožef Stefan" (Author)
ID Klančnik, Anja (Author)
ID Štrancar, Janez, Institut "Jožef Stefan" (Author)
ID Sabotič, Jerica, Institut "Jožef Stefan" (Author) |
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| Files: |  URL - Source URL, visit https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1751-7915.70040
 PDF - Presentation file, download (4,70 MB)
MD5: 530BAC97D583AC6A949A67BBD7D469CA
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  IJS - Jožef Stefan Institute
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| Abstract: | Listeria monocytogenes is a pathogenic bacterium that can form biofilms in food processing plants, allowing the bacteria to survive despite the control measures applied. As the surface of the bacteria is covered with versatile polysaccharides and proteins, these influence the interactions of the bacterium with any surface. The unique properties and high stability of fungal proteins make them good candidates for the control of bacteria by targeting surface structures. We screened a group of fungal lectins and protease inhibitors from different fungal species, protein folds and known targets for their antibacterial and antibiofilm activity against model strains of Listeria innocua and Listeria monocytogenes. Several of them significantly decreased the viability of biofilm bacteria, but had no effect on bacterial growth parameters at 37°C and thus had no antibacterial activity. Fungal lectins significantly impaired biofilm development even at room temperature, which was attributed to exposure to lectins during adhesion. The tested fungal proteins also reduced biofilm development on biological model surfaces. The observed antibiofilm activity of fungal proteins suggests that they have the potential to modulate interactions between bacteria and/or between bacteria and surfaces, which could be used in the future to reduce surface contamination by Listeria. |
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| Keywords: | Listeria monocytogenes, biofilm |
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| Submitted for review: | 20.08.2024 |
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| Article acceptance date: | 17.10.2024 |
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| Publication date: | 30.11.2024 |
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| Publisher: | Wiley |
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| Year of publishing: | 2024 |
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| Number of pages: | str. 1-13 |
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| Numbering: | Vol. 17, issue 12, [article no.] e70040 |
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| Source: | ZDA |
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| PID: | 20.500.12556/DiRROS-21194  |
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| UDC: | 577 |
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| ISSN on article: | 1751-7915 |
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| DOI: | 10.1111/1751-7915.70040 |
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| COBISS.SI-ID: | 217485315 |
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| Copyright: | © 2024 The Author(s). |
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| Note: | Nasl. z nasl. zaslona;
Soavtorji iz Slovenije: Meta Sterniša, Blaž Jug, Tanja Zupan, Tjaša Peternel, Aleksandar Sebastijanović, Milica Perišić Nanut, Katarina Karničar, Ajda Taler-Verčič, Dušan Turk, Anja Klančnik, Janez Štrancar, Jerica Sabotič;
Opis vira z dne 3. 12. 2024;
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| Publication date in DiRROS: | 13.01.2025 |
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| Views: | 40 |
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| Downloads: | 13 |
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