| Title: | TGA transcription factors : structural characteristics as basis for functional variability |
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| Authors: | ID Tomaž, Špela (Author)
ID Gruden, Kristina (Author)
ID Coll Rius, Anna (Author) |
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| Files: |  URL - Source URL, visit https://doi.org/10.3389/fpls.2022.935819
URL - Source URL, visit https://www.frontiersin.org/articles/10.3389/fpls.2022.935819/full#supplementary-material
 PDF - Presentation file, download (2,85 MB)
MD5: C53845CDD0A33CF31BE6284556872FE4
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| Language: | English |
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| Typology: | 1.02 - Review Article |
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| Organization: |  NIB - National Institute of Biology
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| Abstract: | TGA transcription factors are essential regulators of various cellular processes, their activity connected to different hormonal pathways, interacting proteins and regulatory elements. Belonging to the basic region leucine zipper (bZIP) family, TGAs operate by binding to their target DNA sequence as dimers through a conserved bZIP domain. Despite sharing the core DNA-binding sequence, the TGA paralogues exert somewhat different DNA-binding preferences. Sequence variability of their N- and C-terminal protein parts indicates their importance in defining TGA functional specificity through interactions with diverse proteins, affecting their DNA-binding properties. In this review, we provide a short and concise summary on plant TGA transcription factors from a structural point of view, including the relation of their structural characteristics to their functional roles in transcription regulation. |
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| Keywords: | DOG1 domain, functional variability, intrinsically disordered regions, plant transcription regulation, post-translational modifications, structural characteristics, TGA transcription factors |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 26.07.2022 |
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| Year of publishing: | 2022 |
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| Number of pages: | str. 1-12 |
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| Numbering: | Vol. 13 |
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| PID: | 20.500.12556/DiRROS-20102  |
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| UDC: | 576 |
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| ISSN on article: | 1664-462X |
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| DOI: | 10.3389/fpls.2022.935819 |
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| COBISS.SI-ID: | 121573891 |
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| Note: | Nasl. z nasl. zaslona;
Opis vira z dne 16. 9. 2022;
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| Publication date in DiRROS: | 05.08.2024 |
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| Views: | 303 |
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| Downloads: | 265 |
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