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Title:Awake craniotomy for operative treatment of brain gliomas - experience from University Medical Centre Ljubljana
Authors:ID Žele, Tilen (Author)
ID Velnar, Tomaž (Author)
ID Koritnik, Blaž (Author)
ID Bošnjak, Roman (Author)
ID Markovič Božič, Jasmina (Author)
Files:URL URL - Source URL, visit https://www.radioloncol.com/index.php/ro/article/view/3978/5157
 
.pdf PDF - Presentation file, download (2,36 MB)
MD5: B67EBD4AA1918660902E5F8E330F7E29
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:Background. Awake craniotomy is a neurosurgical technique that allows neurophysiological testing with patient cooperation during the resection of brain tumour in regional anaesthesia. This allows identification of vital functional (i.e. eloquent) brain areas during surgery and avoidance of their injury. The aim of the study was to present clinical experience with awake craniotomy for the treatment of gliomas at the University Medical Centre Ljubljana from 2015 to 2019.Patients and methods. Awake craniotomy was considered in patients with a gliomas near or within the language brain areas, in all cases of insular lesions and selected patients with lesions near or within primary motor brain cortex. Each patient was assessed before and after surgery.Results. During the 5-year period, 24 awake craniotomies were performed (18 male and 6 female patients; average age 41). The patient’s cooperation, discomfort and perceived pain assessed during the awake craniotomy were in majority of the cases excellent, slight, and moderate, respectively. After surgery, mild neurological worsening was observed in 13% (3/24) of patients. Gross total resection, in cases of malignant gliomas, was feasible in 60% (6/10) and in cases of low-grade gliomas in 29% (4/14). The surgery did not have important negative impact on functional status or quality of life as assessed by Karnofsky score and Short-Form 36 health survey, respectively (p > 0.05). Conclusions. The results suggest that awake craniotomy for treatment of gliomas is feasible and safe neurosurgical technique. The proper selection of patients, preoperative preparation with planning, and cooperation of medical team members are necessary for best treatment outcome.
Keywords:awake craniotomy, surgery of gliomas, intraoperative neurophysiological testing, primary brain tumours, clinical experiences
Publication status:Published
Publication version:Version of Record
Publication date:01.06.2023
Publisher:Association of Radiology and Oncology
Year of publishing:2023
Number of pages:str. 191-200
Numbering:Vol. 57, no. 2
Source:Ljubljana
PID:20.500.12556/DiRROS-19842 New window
UDC:616-089.888.5
ISSN on article:1318-2099
DOI:10.2478/raon-2022-0052 New window
COBISS.SI-ID:165072899 New window
Copyright:by Authors
Note:Soavtorji: Tomaz Velnar, Blaz Koritnik, Roman Bosnjak, Jasmina Markovic Bozic;
Publication date in DiRROS:25.07.2024
Views:313
Downloads:412
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Keywords:kraniotomija v budnem stanju klinične izkušnje, kirurgija gliomov, intraoperativno nevrofiziološko testiranje, primarni možganski tumorji


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