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Title:Bleomycin electrosclerotherapy (BEST) for the treatment of vascular malformations : an International Network for Sharing Practices on Electrochemotherapy (InspECT) study group report
Authors:ID Muir, Tobian (Author)
ID Bertino, Giulia (Author)
ID Grošelj, Aleš (Author)
ID Ratnam, Lakshmi (Author)
ID Kis, Erika (Author)
ID Odili, Joy (Author)
ID McCafferty, Ian (Author)
ID Wohlgemuth, Walter A (Author)
ID Čemažar, Maja (Author)
ID Krt, Aljoša (Author)
ID Omerzel, Maša (Author)
ID Zanasi, Alessandro (Author)
ID Battista, Michela (Author)
ID De Terlizzi, Francesca (Author)
ID Campana, Luca Giovanni (Author)
ID Serša, Gregor (Author)
Files:.pdf PDF - Presentation file, download (649,88 KB)
MD5: 12CF982475ED52E2696821292FA13431
 
Language:English
Typology:1.02 - Review Article
Organization:Logo OI - Institute of Oncology
Abstract:Biomedical applications of electroporation are expanding out of the field of oncology into vaccination, treatment of arrhythmias and now in the treatment of vascular malformations. Bleomycin is a widely used sclerosing agent in the treatment of various vascular malformations. The application of electric pulses in addition to bleomycin enhances the effectiveness of the drug, as demonstrated by electrochemotherapy, which utilizes bleomycin in the treatment of tumors. The same principle is used in bleomycin electrosclerotherapy (BEST). The approach seems to be effective in the treatment of low-flow (venous and lymphatic) and, potentially, even high-flow (arteriovenous) malformations. Although there are only a few published reports to date, the surgical community is interested, and an increasing number of centers are applying BEST in the treatment of vascular malformations. Within the International Network for Sharing Practices on Electrochemotherapy (InspECT) consortium, a dedicated working group has been constituted to develop standard operating procedures for BEST and foster clinical trials. By treatment standardization and successful completion of clinical trials demonstrating the effectiveness and safety of the approach, higher quality data and better clinical outcomes may be achieved.
Keywords:vascular malformations, electrosclerotherapy, bleomycin
Publication status:Published
Publication version:Version of Record
Publication date:01.01.2023
Publisher:Association of Radiology and Oncology
Year of publishing:2023
Number of pages:str. 141-149
Numbering:Vol. 57, no. 2
Source:Ljubljana
PID:20.500.12556/DiRROS-19832 New window
UDC:616-006
ISSN on article:1318-2099
DOI:10.2478/raon-2023-0029 New window
COBISS.SI-ID:159007235 New window
Copyright:by Authors
Publication date in DiRROS:25.07.2024
Views:545
Downloads:170
Metadata:XML DC-XML DC-RDF
:
MUIR, Tobian, BERTINO, Giulia, GROŠELJ, Aleš, RATNAM, Lakshmi, KIS, Erika, ODILI, Joy, MCCAFFERTY, Ian, WOHLGEMUTH, Walter A, ČEMAŽAR, Maja, KRT, Aljoša, OMERZEL, Maša, ZANASI, Alessandro, BATTISTA, Michela, DE TERLIZZI, Francesca, CAMPANA, Luca Giovanni and SERŠA, Gregor, 2023, Bleomycin electrosclerotherapy (BEST) for the treatment of vascular malformations : an International Network for Sharing Practices on Electrochemotherapy (InspECT) study group report. Radiology and oncology [online]. 2023. Vol. 57, no. 2, p. 141–149. [Accessed 4 April 2025]. DOI 10.2478/raon-2023-0029. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=19832
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Keywords:žilne malformacije, elektroskleroterapija, bleomycin


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