| Title: | Surgical treatment of malignant pleural mesothelioma |
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| Authors: | ID Eržen, Janez (Author)
ID Vidmar, Stanko (Author)
ID Sok, Mihael (Author)
ID Debeljak, Andrej (Author)
ID Kecelj, Peter (Author)
ID Kovač, Viljem (Author)
ID Stanovnik, Marjeta (Author)
ID Rott, Tomaž (Author)
ID Kern, Izidor (Author) |
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| Files: |  PDF - Presentation file, download (82,10 KB)
MD5: 4F59CCA8F92DE43AA1534CF667F108D2
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  OI - Institute of Oncology
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| Abstract: | Background. The aim of the study was to identify perioperative morbidity and mortality, the category and mode of adjuvant treatment, local recurrence and survival in patients treated by extrapleural pneumonectony (EPP) for malignantpleural mesothelioma (NLPM). Methods. From 2000 to 2003, 18 patients with MPM were referred to the Department of Thoracic Surgery in Ljubljana, and17 of them were operated on. Two patients underwent explorative thoracotomy, and 15 patients were evaluated. Five female and nine male patients (aged 52-68 years) were treated by EPP and one male patient by pleurectomy. Eight patients received both adjuvant chemotherapy (ChT) and radiotherapy (RT), with cisplatin 100 mg/m2 + mitomycin C 6-10 mg/m2 gemcitabine 1000 mg/m2 and external beam radiation with 24 Gy - 58 Gy respectively, three patients received no adjuvant therapy, three patients weretreated by adjuvant ChT, two of them were given cisplatin 100 mg/m2 + mitomycin C 6-10 mg/m2, and one patient cisplatin 100 mg/m2 on the first day and gemcitabine 250 mg/rn2 in prolonged 6 hours infusion on the first and on the eighth day. One patient was treated only by adjuvant RT. Results. There were no perioperative deaths and the postoperative morbidity was 42%. Of the 15 evaluable patients, and in the median follow up of 40 months (28-64), we noticed nine (60.0%) recurrences, seven local and two abdominal. Eight (53.3%)patients died, all because of the local progress of disease. (Abstract truncated at 2000 characters) |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 01.01.2005 |
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| Publisher: | Association of Radiology and Oncology |
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| Year of publishing: | 2005 |
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| Number of pages: | str. 123-131 |
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| Numbering: | Letn. 39, št. 2 |
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| Source: | Ljubljana |
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| PID: | 20.500.12556/DiRROS-18168  |
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| UDC: | 616.2 |
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| ISSN on article: | 1318-2099 |
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| COBISS.SI-ID: | 19765721 |
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| Copyright: | by Authors |
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| Note: | BSDOCID115521;
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| Publication date in DiRROS: | 14.02.2024 |
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| Views: | 551 |
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| Downloads: | 128 |
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| Metadata: |    |
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