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Title: Radiographic, computed tomographic and magnetic resonance imaging appearances of primary V-cutting zone of resorption of lumbar vertebral body in Paget's disease Authors: ID Jevtič, Vladimir (Author) Files: PDF - Presentation file, download (6,47 MB) MD5: 872831CBD782628DD4CA1B17C66ADE79   Language: English Typology: 1.04 - Professional Article Organization: OI - Institute of Oncology Abstract: Background. Paget's disease of bone typically demonstrates three evolutionary phases with the characteristic radiographic findings. The incipient stage is manifested by an advancing lytic zone of resorption. Unlike the skull and the long bones the primary advancing zone of rarefication has not been clearly demonstrated within the spine and pelvis. Case report. A 62-year-old man with histologically proved polyostotic Paget's disease was admitted to the hospitaldue to the exacerbation of pain at the toracolumbar junction with deterioration during the night. Due to slight elevation of acid phosphatase and clinical signs indicating prostatic hypertrophy the possibility of metastatic prostatic carcinoma has been raised. A bone scintigraphy with technetium phosphonate showed the expected marked increased uptake affecting numerous bones with the typical radiographic signs of Paget's disease. Besidesthese findings, there was also moderate focal accumulation within the right dorsal half of the vertebral body of L1. Conventional tomography, computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated theprimary cutting zone of resorption affecting the same region. Conclusions. We present a unique case of Paget's disease with primary V-cutting zone withinthe undeformed vertebral body of L1 and spontaneous progression to the midphase of the disease on a three year follow-up. Publication status: Published Publication version: Version of Record Publication date: 01.01.2004 Publisher: Association of Radiology and Oncology Year of publishing: 2004 Number of pages: str. 333-338 Numbering: Letn. 38, št. 4 Source: Ljubljana PID: 20.500.12556/DiRROS-18160  UDC: 616-07 ISSN on article: 1318-2099 COBISS.SI-ID: 19027161  Copyright: by Authors Note: BSDOCID112283; Publication date in DiRROS: 13.02.2024 Views: 403 Downloads: 124 Metadata:    Cite this work Plain text BibTeX EndNote XML EndNote/Refer RIS ABNT ACM Ref AMA APA Chicago 17th Author-Date Harvard IEEE ISO 690 MLA Vancouver : Copy citation

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Record is a part of a journal

Title:	Radiology and oncology
Shortened title:	Radiol. oncol.
Publisher:	Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:	1318-2099
COBISS.SI-ID:	32649472

Secondary language

Language:	Slovenian
Title:	Radiografski, računalniškotomografski in magnetnoresonančni znaki primarne cone kostne resorpcije v korpusu ledvenega vretenca pri Pagetovi bolezni
Abstract:	Izhodišča. Potek Pagetove bolezni kosti ima tri razvojne faze z značilnimi radiografskimi znaki. V začetni fazi je prisotna napredujoča cona kostne resorpcije. Primarna napredujoča cona osteolize ni bila nikoli jasno prikazanana hrbtenici in medenici, kot je bila na lobanji in dolgih kosteh. Prikaz primera. 62-letni bolnik s histološko potrjeno diagnozo poliostotske Pagetove bolezni je bil sprejet v bolnico zaradi bolečin v višini torakolumbalnega prehoda, ki so se ponoči stopnjevale. Zaradi zmerno zvišane kisle fosfataze ter kliničnih znakov hipertrofije prostate je bil postavljen sum na karcinom prostate. Kostna scintigrafija s tehnecijevim fosfonatom je pokazala pričakovano nabiranje radiofarmaka na številnih kostnih elementih s tipičnimi radiografskimi znaki Pagetove bolezni. Razen omenjenega se je pokazalo zmerno žariščno nabiranje radiofarmaka tudi v desni dorzalni polovicikorpusa vretenca L1. V istem področju so klasična tomografija, računalniška tomografija (CT) ter magnetnoresonančna tomografija (MRI) prikazale primarno cono kostne resorpcije. Zaključki. Prikazan je edinstven primer Pagetove bolezni s primarno cono kostne resorpcije v morfološko nespremenjenem korpusu vretenca L1. Po treh letih zasledovanja je prišlo do spontanega napredovanja v srednjo fazo bolezni.

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