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Title:Long term follow-up after radiosynovectomy with yttrium 90 in patients with different rheumatic diseases
Authors:ID Golja, Mojca (Author)
ID Budihna, Nataša (Author)
ID Batagelj, Igor (Author)
Files:.pdf PDF - Presentation file, download (940,70 KB)
MD5: EC63F7D448DFBC92C6459293149B4F49
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:The aim of the retrospective study was to evaluate the efficacy of radiosynovectomy (with yttrium 90) mainly in patients with rheumatoid arthritis, less with some other rheumatic diseases. The evaluation period varied from half to nine years. The procedure was performed in 273 patients (225 females, 48 males) or in 463 joints (402 knees, 61 shoulders and ankles).The effects was evaluated by change in degree of morning stiffiness, pain and swelling (score from 0 to 9). Very good results were obtained in 69 (15%), good in 142 (30.5%), moderate in 197 (42.5%) and no effect in 55 (12%) joints. Six months after the procedure 38 joints (8%), half to two years after221 joint (48%) were in good remission, after 3 to 4 years 95 joints (20%), after 5 to 6 years 57 joints (12%) were well, 7 to 9 years later 52 joints (11%) showed no signs of arthritis. Joint pain and swelling were the most frequent procedure complications (5.6%). In two patients with additional immunomodulating therapy chronic myeloid and lymphocityc leukaemia were diagnosed. Radiosynovectomy is considered to be an effective and safe treatment for synovitis indifferent rheumatic diseases.
Publication status:Published
Publication version:Version of Record
Publication date:01.01.1997
Publisher:Slovenian Medical Society - Section of Radiology ; Croatian Medical Association - Croatian Society of Radiology
Year of publishing:1997
Number of pages:str. 353-357
Numbering:Letn. 31, št. 4
Source:Ljubljana
PID:20.500.12556/DiRROS-17869 New window
UDC:61
ISSN on article:1318-2099
COBISS.SI-ID:7834585 New window
Copyright:by Authors
Note:BSDOCID35238;
Publication date in DiRROS:18.01.2024
Views:573
Downloads:121
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Title:[Radiosinoviektomija z itrijem 90 pri bolnikih z različnimi revmatskimi boleznimi: ugotavljanje trajanja terapevtskega učinka]
Abstract:Cilj retrospektivne študije je bil oceniti učinek izotopske sinovektomije z itrijem 90 predvsem pri bolnikih z revmatoidnim artritisom inmanj z nekaterimirevmatičnimi boleznimi. Bolnike smo opazovali v obdobju od pol do devet let. Poseg je bil napravljen pri 273 bolnikih (225 žensk, 48 moških) oziroma na 463 sklepih (402 na kolenih, 61 na ramenih in gležnjih). Učinek smoocenjevali s spremembo stopnje jutranje okorelnosti , bolečine in otekline sklepa (od 0 do 9). Zelo dobre rezulate smo dosegli na 69 (15%), dobre na 142 (30,5%), srednje dobre na 197 sklepih (42,5%), na 55 sklepih ni bilo učinka (12%). Pol leta po posegu je bilo 38 sklepov (8%) v remisiji, pol do dve leti 221 (48%), po 3 do 4 letih 95 (20%), po 5 do 6 letih je bilo 57 sklepov brez znakov vnetja (12%), po 7 do 9 letih pa še 52 (11%). Najpogostejši zapleti po sinovektomiji so bile bolečine in otekline sklepov (5,6%). Pri dveh bolnicah, ki sta dobivali tudi imunomodulirajoča zdravila, smo odkrili kronično mieloično oziroma limfatično levkemijo. Izotopska sinovektomija je torej učinkovito in varno zdravljenje sinovitisa pri različnih boleznih.


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