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Title:Cytology of mediastinal tumors
Authors:ID Mermolja, Milivoj (Author)
ID Kern, Izidor (Author)
ID Terčelj-Zorman, Marjeta (Author)
ID Jereb, Marjan (Author)
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MD5: 7A5A3781DB04B5785F8493D0CBE2F848
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo OI - Institute of Oncology
Abstract:Our experience with cytological examinations of tumorous mediastinal lesions is evaluated. A group of 117 patients with mediastinal tumor have been included into the study. Among them carcinomas prevailed (60,7%), followed by lymphomas (18,8%), other tumors (15.4%) and thymic neoplasms (5.1%). Malignantor suspicious cells were found in 77.4% of patients with carcinoma. The cells indicating a possibility of non-Hodgkin's lymphoma were found in 9 out of 14 patients. In 5 out of 6 thymic neoplasms the cytological pattern wasconsistent with the diagnosis of thymic neoplasm. One case of thymoma was cytologically falsely diagnosed as malignant lymphoma. One case of neurofibroma was falsely diagnosed as adenocarcinoma. The sensitivity of cytological examinations was 67.5%. If 18 patients with diagnostically unsatisfactory material were excluded from the analysis, the sensitivity wouldincrease to 80.8%. Owing to the wide variety of primary and metastatic tumors that can occur in the mediastinum, apart from the routine cytological techniques, additional staining methods should be used. For final cytological diagnosis the integration of cytological findings with clinical and radiological data is often required. Owing to the characteristics of the obtained material and biological behaviour of some mediastinal tumors, some tumors cannot be definitively diagnosed by cytological examinations alone.
Publication status:Published
Publication version:Version of Record
Publication date:01.01.1997
Publisher:Slovenian Medical Society - Section of Radiology ; Croatian Medical Association - Croatian Society of Radiology
Year of publishing:1997
Number of pages:str. 380-383
Numbering:Letn. 31, št. 4
Source:Ljubljana
PID:20.500.12556/DiRROS-17868 New window
UDC:616-006
ISSN on article:1318-2099
COBISS.SI-ID:7829465 New window
Copyright:by Authors
Note:BSDOCID35243;
Publication date in DiRROS:18.01.2024
Views:614
Downloads:148
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:Slovenian
Title:[Citologija mediastinalnih tumorjev]
Abstract:Avtorji predstavijo izkušnje Kliničnega oddelka za pljučne bolezni in alergična stanja Golnik s citološkimi pregledi mediastinalnih tumorjev. V retrospektivno študijo je bilo vključenih 117 bolnikov z mediastinalnim tumorjem. Najpogostejši so bili karcinomi (60,7%0, sledijo limfomi (18,8%), drugi tumorji (15,4%), in timične neoplazme (5,1%). Maligne ali sunljive celice so našli pri 77,4% bolnikov s karcinomom. Celice, ki so dopuščale možnost ne-Hodgkinovega limfoma, so našli pri 9 od 14 bolnikov. Pri 5 od 6 primerov timičnih neplazem je bila citološka slika skladna z diagnozo timične neoplazme. En primer timoma je bil citološko napačno opredeljen kot maligni limfom, en primer neurofibroma pa je bil napačno opredeljen kot adenokarcinom.Senzitivnost citoloških pregledov je bila 67,5%. Če bi 18 bolnikov, pri katerih dobljeni material ni bil ustrezen, izključili iz analize, bi senzitivnost zrasla na 80,8%. Ker so primarni in metastatski tumorji, ki se pojavljajo v mediastinumu zelo raznoliki, so za njihovo opredelitev poleg rutinskih citoloških tehnik potrebne tudi dodatne metode barvanja. Za končno citološko diagnozo je nujno poznati tudi klinične podatke in podatke slikovnih diagnostičnih metod. Glede na značilnosti dobljenjega materiala in biološko obnašanje nekaterih mediastinalnih tumorjev vseh ni možno definitivno opredeliti na osnovi citološkega pregleda.


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