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Title:Kirurško zdravljenje malignega melanoma
Authors:ID Planinšek, Franc (Author)
ID Arnež, Zoran M. (Author)
Files:.pdf PDF - Presentation file, download (289,51 KB)
MD5: 2331207BA5FE14D820D1A08F2BFD05DC
 
Language:Slovenian
Typology:1.02 - Review Article
Organization:Logo OI - Institute of Oncology
Abstract:Incidenca in umrljivost zaradi malignega melanoma (MM) rasteta v svetu in pri nas. Kljub temu je prognoza bolezni danes boljša zaradi zgodnejšega odkrivanjaMM. MM je v zgodnjem kliničnem obdobju ozdravljiv s preprostim kirurškim izrezom sumljivo spremenjenega tkiva z varnostnim robom. Primerjava debeline tumorja in uspešnosti lokalnega nadzora bolezni ob izrezih različno širokega varnostnega pasu je zožila varnostni pas iz prejšnjih 5 in več cm ("široka ali razširjena ekscizija") na 1 do 2 cm. Zato lahko danes pri večini bolnikov z malignim melanomom zapremo nastalo tkivno vrzel po odstranitvi tumorja zgolj z neposrednim šivom rane, le redko pa s prostimi kožnimi presadki in lokalnimi, oddaljenimi ali prostimi režnji. Izbirna (elektivna) odstranitev področnih bezgavk ni smiselna. Za terapevtsko odstranitev področnih bezgavk se odločimo pri pozitivni varovalni bezgavki oz. pri na otippovečanih regionalnih bezgavkah brez znakov sistemskega razsoja. Osamljene(solitarne) oddaljene zasevke odstranimo izjemoma in le v tistih primerih, ko postanejo simptomatski. (npr.zvišan intrakranialni tlak, mehanskaovira v prehodnosti cevastih organov, motnje dihanja, pojav zlatenice).
Publication status:Published
Publication version:Version of Record
Publication date:01.01.1999
Publisher:Slovenian Medical Association - Slovenian Association of Radiology, Nuclear Medicine Society, Slovenian Society far Radiotherapy and Oncology, and Slovenian Cancer Society
Year of publishing:1999
Number of pages:str. S40-4
Numbering:Letn. 33, suppl. 1
Source:Ljubljana
PID:20.500.12556/DiRROS-17366 New window
UDC:616-006
ISSN on article:1318-2099
COBISS.SI-ID:10733529 New window
Copyright:by Authors
Note:Simpozij o malignem melanomu in kožnem raku; BSDOCID48314;
Publication date in DiRROS:27.11.2023
Views:527
Downloads:129
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Record is a part of a journal

Title:Radiology and oncology
Shortened title:Radiol. oncol.
Publisher:Slovenian Medical Society - Section of Radiology, Croatian Medical Association - Croatian Society of Radiology
ISSN:1318-2099
COBISS.SI-ID:32649472 New window

Secondary language

Language:English
Title:Surgical treatment of malignant melanoma
Abstract:Although the incidence and the mortality rates of malignant melanoma (MM) havebeen increasing worldwide and in Slovenija for the last several decades, the survival rates are improving. The apparent contradiction may be expained by the increase in early diagnnosis of MM. If detected early in its clinical course MM can be cured by a simple surgical excision in majority of patients. The decision about the margins of the surgical excision of the primary melanoma site has been made more rational through correlations of rates of local control with different margins of resection in relation to the domianantprognostic factor for localized melanoma, the thickness of the lesion. When possible, primary closure of the post-excisional defect should beperformed. If primary closure is impossible, the wound may be closed by split or full thickness skin grafting, local, regional or free flaps. Electivedissection has not been shown in prospective randomized trials to alter survival significantly. Surgical treatment of distant metastases is indicated only as palliation of a solitary symptomatic lesion (brain metastases, lung or gastrointestinal metastases).


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