| Title: | A method for the immobilization of chitosan onto urinary catheters |
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| Authors: | ID Vesel, Alenka, Institut Jožef Stefan (Author)
ID Recek, Nina, Institut Jožef Stefan (Author)
ID Zaplotnik, Rok, Institut Jožef Stefan (Author)
ID Kurinčič, Albert (Author)
ID Kuzmič, Katja (Author)
ID Fras Zemljič, Lidija (Author) |
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| Files: |  PDF - Presentation file, download (6,47 MB)
MD5: 54C1D71B0299D90A95E4DB7D7B5510BA
 URL - Source URL, visit https://www.mdpi.com/1422-0067/23/23/15075/pdf?version=1669883521
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  IJS - Jožef Stefan Institute
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| Abstract: | A method for the immobilization of an antibacterial chitosan coating to polymeric urinary medical catheters is presented. The method comprises a two-step plasma-treatment procedure, followed by the deposition of chitosan from the water solution. In the first plasma step, the urinary catheter is treated with vacuum-ultraviolet radiation to break bonds in the polymer surface film and create dangling bonds, which are occupied by hydrogen atoms. In the second plasma step, polymeric catheters are treated with atomic oxygen to form oxygen-containing surface functional groups acting as binding sites for chitosan. The presence of oxygen functional groups also causes a transformation of the hydrophobic polymer surface to hydrophilic, thus enabling uniform wetting and improved adsorption of the chitosan coating. The wettability was measured by the sessile-drop method, while the surface composition and structure were measured by X-ray photoelectron spectroscopy and Fourier-transform infrared spectroscopy. Non-treated samples did not exhibit successful chitosan immobilization. The effect of plasma treatment on immobilization was explained by noncovalent interactions such as electrostatic interactions and hydrogen bonds. |
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| Keywords: | polymer, chitosan immobilization, adhesion, plasma-surface modification, biopolymers |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Article acceptance date: | 28.11.2022 |
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| Publication date: | 01.12.2022 |
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| Year of publishing: | 2022 |
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| Number of pages: | str. 1-18 |
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| Numbering: | Vol. 23 |
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| PID: | 20.500.12556/DiRROS-15884  |
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| UDC: | 533 |
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| ISSN on article: | 1422-0067 |
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| DOI: | 10.3390/ijms232315075 |
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| COBISS.SI-ID: | 131927043 |
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| Note: | Nasl. z nasl. zaslona;
Soavtorji: Nina Recek, Rok Zaplotnik, Albert Kurinčič, Katja Kuzmič, Lidija Fras Zemljič;
Opis vira z dne 1. 12. 2022;
Št. članka: 15075;
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| Publication date in DiRROS: | 05.12.2022 |
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| Views: | 856 |
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| Downloads: | 449 |
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