| Title: | Patch testing with the European baseline series and 10 added allergens : single centre study of 748 patients |
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| Authors: | ID Bizjak, Mojca, Klinika Golnik (Author)
ID Adamič, Katja, Klinika Golnik (Author)
ID Bajrović, Nisera, Klinika Golnik (Author)
ID Eržen, Renato, Klinika Golnik, Bolnišnica Topolšica (Author)
ID Jošt, Maja, Klinika Golnik (Author)
ID Kopač, Peter, Klinika Golnik, Medicinska fakulteta UL (Author)
ID Košnik, Mitja, Klinika Golnik, Medicinska fakulteta UL (Author)
ID Lalek, Nika, Klinika Golnik (Author)
ID Zidarn, Mihaela, Klinika Golnik, Medicinska fakulteta UL (Author)
ID Dinevski, Dejan (Author) |
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| Files: |  URL - Source URL, visit https://onlinelibrary.wiley.com/doi/epdf/10.1111/cod.14178
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| Language: | English |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: |  UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
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| Abstract: | Background. The European baseline series (EBS) of contact allergens is subject to change. An allergen is considered for inclusion when routine patch testing of patients with suspected contact dermatitis results in ≥ 0.5% prevalence rate. Objectives. We aimed to determine the frequency of sensitizations to 30 EBS allergens and 10 locally added allergens. Additionally, we assessed the strength and evolution of reactions to all tested allergens and co-reactivity of additional allergens. Methods. Patch testing with our baseline series of 40 allergens was done in 748 consecutive adults. Tests were applied to the upper back and removed by patients after 48 hours. Readings were done on day 3 (D3) and D6 or D7 (D6/7). Positive reactions fulfilled the criteria of at least one plus (+) reaction. Retrospective analysis was done. Results. Eight allergens not listed in the EBS had ≥ 0.5% prevalence rate (i.e., cocamidopropyl betaine, thiomersal, disperse blue mix 106/124, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, propylene glycol, Compositae mix II, and dexamethasone-21-phosphate), and 16.6% of positive reactions would have been missed without D6/7 readings. Conclusion. We propose further studies to evaluate whether cocamidopropyl betaine, disperse blue mix 106/124, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, and Compositae mix II need to be added to the EBS. |
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| Keywords: | allergy and immunology -- diagnosis, hypersensitivity -- diagnosis, skin tests, clinical epidemiology, baseline series, contact sensitization, patch tests, simultaneous reactivity |
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| Publication status: | In print |
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| Publication version: | Author Accepted Manuscript |
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| Place of publishing: | Velika Britanija |
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| Publisher: | Wiley |
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| Year of publishing: | 2022 |
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| Number of pages: | str. [1-21] |
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| Numbering: | Vol. 87 |
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| PID: | 20.500.12556/DiRROS-15228  |
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| UDC: | 616-097 |
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| ISSN on article: | 1600-0536 |
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| DOI: | 10.1111/cod.14178 |
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| COBISS.SI-ID: | 112721411 |
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| Note: | Nasl. z nasl. zaslona;
Soavtorji: Katja Adamič, Nissera Bajrović, Renato Eržen, Maja Jošt, Peter Kopač, Mitja Košnik, Nika Lalek, Mihaela Zidarn, Dejan Dinevski;
Opis vira z dne 24. 6. 2022;
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| Publication date in DiRROS: | 24.06.2022 |
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| Views: | 970 |
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| Downloads: | 354 |
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