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Title:Covid-19 pulmonary pathology : the experience of European pulmonary pathologists throughout the first two waves of the pandemic
Authors:Fortarezza, Francesco (Author)
Pezzuto, Federica (Author)
Hofman, Paul (Author)
Kern, Izidor (Author)
Panizo, Angel (Author)
Thüsen, Jan von der (Author)
Timofeev, Sergei (Author)
Gorkiewicz, Gregor (Author)
Berezowska, Sabina (Author)
Level, Laurence de (Author)
Ortiz-Villalón, Cristian (Author)
Lunardi, Francesca (Author)
Calabrese, Fiorella (Author)
Tipology:1.01 - Original Scientific Article
Organisation:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Autoptic studies of patients who died from COVID-19 constitute an important step forward in improving our knowledge in the pathophysiology of SARS-CoV-2 infection. Systematic analyses of lung tissue, the organ primarily targeted by the disease, were mostly performed during the first wave of the pandemic. Analyses of pathological lesions at different times offer a good opportunity to better understand the disease and how its evolution has been influenced mostly by new SARS-CoV-2 variants or the different therapeutic approaches. In this short report we summarize responses collected from a questionnaire survey that investigated important pathological data during the first two pandemic waves (spring-summer 2020; autumn-winter 2020–2021). The survey was submitted to expert lung pathologists from nine European countries involved in autoptic procedures in both pandemic waves. The frequency of each lung lesion was quite heterogeneous among the participants. However, a higher frequency of pulmonary superinfections, both bacterial and especially fungal, was observed in the second wave compared to the first. Obtaining a deeper knowledge of the pathological lesions at the basis of this complex and severe disease, which change over time, is crucial for correct patient management and treatment. Autoptic examination is a useful tool to achieve this goal.
Keywords:COVID-19, SARS-CoV-2, autopsy, lung - pathology, pulmonary aspergillosis
Year of publishing:2022
COBISS_ID:92729091 Link is opened in a new window
ISSN on article:2075-4418
DOI:10.3390/diagnostics12010095 Link is opened in a new window
Note:Nasl. z nasl. zaslona; Soavtor iz Slovenije: Izidor Kern; Opis vira z dne 5. 1. 2022; Št. članka: 95;
Files:.pdf PDF - Presentation file, download (2,30 MB)
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Rights:© 2022 by the authors
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License:CC BY 4.0, Creative Commons Attribution 4.0 International
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:01.01.2022