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Title:Absence of an aging-related increase in fibre type grouping in athletes and non-athletes
Authors:ID Messa, Guy A. M. (Author)
ID Piasecki, Mathew (Author)
ID Rittweger, Joern (Author)
ID McPhee, Jamie (Author)
ID Koltai, Erika (Author)
ID Radak, Zsolt (Author)
ID Šimunič, Boštjan (Author)
ID Heinonen, Ari (Author)
ID Suominen, Harri (Author)
ID Korhonen, Marko T. (Author)
ID Degens, Hans (Author)
Files:.pdf PDF - Presentation file, download (936,83 KB)
MD5: 07C77CBC93B0973650433DB03E67751F
 
URL URL - Source URL, visit https://doi.org/10.1111/sms.13778
 
URL URL - Source URL, visit https://onlinelibrary.wiley.com/doi/abs/10.1111/sms.13778
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo ZRS Koper - Science and Research Centre Koper
Abstract:The ageing-related loss of muscle mass is thought to be partly attributable to motor neuron loss and motor unit remodelling that result in fibre type grouping. We examined fibre type grouping in 19- to 85-year-old athletes and non-athletes and evaluated to which extent any observed grouping is explained by the fibre type composition of the muscle. Since regular physical activity may stimulate reinnervation, we hypothesised that fibre groups are larger in master athletes than in age-matched non-athletes. Fibre type grouping was assessed in m. vastus lateralis biopsies from 22 young (19-27 years) and 35 healthy older (66-82 years) non-athletes, and 14 young (20-29 years), 51 middle-aged (38%65 years) and 31 older (66-85 years) athletes. An "enclosed fibre" was any muscle fibre of a particular type surrounded by fibres of the same type only. A fibre type group was defined as a group of fibres with at least one enclosed fibre. Only type II fibre cross-sectional area (FCSA) showed an age-related decline that was greater in athletes (p < 0.001) than in non-athletes (p = 0.012). There was no significant age-related effect on fibre group size or fibre group number in athletes or non-athletes, and the observed grouping was similar to that expected from the fibre type composition. At face value these observations do 1) neither show evidence for an age-related loss and remodelling of motor units nor 2) improved reinnervation with regular physical activity, but 3) histological examination may not reveal the full extent of ageing-related motor unit remodelling.
Keywords:aging, denervation, fibre type, reinnervation, vastus lateralis
Publication status:Published
Publication version:Version of Record
Year of publishing:2020
Number of pages:str. 2057-2069
Numbering:Vol. 30, iss. 11
PID:20.500.12556/DiRROS-13793 New window
UDC:612.74:612.66
ISSN on article:1600-0838
DOI:10.1111/sms.13778 New window
COBISS.SI-ID:26434563 New window
Copyright:2020 The Authors
Note:Nasl. z nasl. zaslona; Opis vira z dne 15. 10. 2020; Soavtorji: Mathew Piasecki, Jörn Rittweger, Jamie S. McPhee, Erika Koltai, Zsolt Radak, Bostjan Simunic, Ari Heinonen, Harri Suominen, Marko T. Korhonen, Hans Degens;
Publication date in DiRROS:24.03.2021
Views:1020
Downloads:785
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Record is a part of a journal

Title:Scandinavian journal of medicine & science in sports
Shortened title:Scand. j. med. sci. sports
Publisher:Blackwell
ISSN:1600-0838
COBISS.SI-ID:517824025 New window

Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:24.07.2020

Secondary language

Language:Undetermined
Keywords:staranje, denervacija, mišična vlakna, reinervacija, vastus lateralis


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