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Title:Continuous glucose monitoring use and glucose variability in pre-school children with type 1 diabetes
Authors:ID Dovč, Klemen (Author)
ID Cargnelutti, Kevin (Author)
ID Šturm, Anže (Author)
ID Šelb, Julij, Klinika Golnik (Author)
ID Bratina, Nataša (Author)
ID Battelino, Tadej (Author)
Files:.pdf PDF - Presentation file, download (738,73 KB)
MD5: A2DB755CCE7EB20130CAE7E91A864D81
 
URL URL - Source URL, visit https://www.sciencedirect.com/science/article/pii/S0168822718310878?via%3Dihub
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Aims. The objective of this nationwide population-based cohort study was to evaluate the correlation between continuous glucose monitoring (CGM) use and glucose variability in pre-schoolers with type 1 diabetes. Methods. We analysed data from the Slovenian National Registry. The primary endpoint was the difference in glucose variability between periods, during which participants were using CGM and periods, during which CGM was not used, over 5 years. Results. A total of 40 children <8 years old were followed for an estimated observational period of 116 patient/years. Mean age at CGM initiation was 3.5 (±1.7) years. Both standard deviation of mean glucose [3.6 mmol/L (3.2–3.9) with CGM and 4.3 mmol/L (3.8–4.7) without CGM, p < 0.001] and coefficient of variation [44.0% (40.4–47.0) with CGM and 46.1% (42.3–49.4) without CGM, p = 0.021] were lower during the periods, when CGM was used. Frequent CGM use (>5 days/week) was associated with a 0.4% [4.4 mmol/mol] reduction in glycated haemoglobin level (7.6% compared to 7.2%, p = 0.047). Conclusions. Our results indicate that the use of CGM was associated with reduced glucose variability during a 5 year follow-up period among pre-schoolers with type 1 diabetes.
Keywords:continuous glucose monitoring, type 1 diabetes, children, insulin therapy
Publication status:Published
Publication version:Version of Record
Place of publishing:Nizozemska
Publisher:Elsevier
Year of publishing:2018
Number of pages:str. 76-80
Numbering:Vol. 147
PID:20.500.12556/DiRROS-12632 New window
UDC:616.379
ISSN on article:0168-8227
DOI:10.1016/j.diabres.2018.10.005 New window
COBISS.SI-ID:5261484 New window
Copyright:© 2018 The Authors
Publication date in DiRROS:12.11.2020
Views:1244
Downloads:791
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Record is a part of a journal

Title:Diabetes research and clinical practice
Shortened title:Diabetes res. clin. pract.
Publisher:Elsevier
ISSN:0168-8227
COBISS.SI-ID:530708 New window

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License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:14.10.2018

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