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Title:Management of a surgical patient with a label of penicillin allergy : narrative review and consensus recommendations
Authors:Savic, Louise C. (Author)
Khan, David A. (Author)
Kopač, Peter (Author)
Clarke, Russel C. (Author)
Cooke, Peter J. (Author)
Dewachter, Pascale (Author)
Ebo, Didier G. (Author)
Garcez, Tomaz (Author)
Garvey, Lene Heise (Author)
Guttormsen, Anne Berit (Author)
Tipology:1.02 - Review Article
Organisation:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Unsubstantiated penicillin-allergy labels are common in surgical patients, and can lead to significant harm through avoidance of best first-line prophylaxis of surgical site infections and increased infection with resistant bacterial strains. Up to 98% of penicillin-allergy labels are incorrect when tested. Because of the scarcity of trained allergists in all healthcare systems, only a minority of surgical patients have the opportunity to undergo testing and de-labelling before surgery. Testing pathways can be modified and shortened in selected patients. A variety of healthcare professionals can, with appropriate training and in collaboration with allergists, provide testing for selected patients. We review how patients might be assessed, the appropriate testing strategies that can be used, and the minimum standards of safe testing.
Keywords:allergy and immunology, drug hypersensitivity, penicillins, antibiotic prophylaxis, surgery, operative surgical procedures, bacterial infections, surgical wound infection, drug provocation testing, surgical procedures
Year of publishing:2019
Source:Velika Britanija
COBISS_ID:2048508529 Link is opened in a new window
ISSN on article:1471-6771
OceCobissID:515369241 Link is opened in a new window
DOI:10.1016/j.bja.2019.01.026 Link is opened in a new window
Note:Soavtor iz Slovenije: P. Kopac; Nasl. z nasl. zaslona; Opis vira z dne 31. 5. 2019;
Files:URL URL - Source URL, visit
Journal:Br. j. anaesth.
Oxford University Press.
Rights:© 2019 British Journal of Anaesthesia
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