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Title:Management of suspected immediate perioperative allergic reactions : an international overview and consensus recommendations
Authors:ID Garvey, Lene Heise (Author)
ID Dewachter, Pascale (Author)
ID Hepner, David L. (Author)
ID Mertes, Paul Michel (Author)
ID Voltolini, Susanna (Author)
ID Clarke, Russel C. (Author)
ID Cooke, Peter J. (Author)
ID Garcez, Tomaz (Author)
ID Guttormsen, Anne Berit (Author)
ID Ebo, Didier G. (Author)
ID Hopkins, Philip M. (Author)
ID Kopač, Peter, Klinika Golnik, Medicinska fakulteta UL (Author)
Files:URL URL - Source URL, visit
Typology:1.02 - Review Article
Organization:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Suspected perioperative allergic reactions are rare but can be life-threatening. The diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct treatment is necessary to ensure a good outcome. A group of 26 international experts in perioperative allergy (anaesthesiologists, allergists, and immunologists) contributed to a modified Delphi consensus process, which covered areas such as differential diagnosis, management during and after anaphylaxis, allergy investigations, and plans for a subsequent anaesthetic. They were asked to rank the appropriateness of statements related to the immediate management of suspected perioperative allergic reactions. Statements were selected to represent areas where there is a lack of consensus in existing guidelines, such as dosing of epinephrine and fluids, the management of impending cardiac arrest, and reactions refractory to standard treatment. The results of the modified Delphi consensus process have been included in the recommendations on the management of suspected perioperative allergic reactions. This paper provides anaesthetists with an overview of relevant knowledge on the immediate and postoperative management of suspected perioperative allergic reactions based on current literature and expert opinion. In addition, it provides practical advice and recommendations in areas where consensus has been lacking in existing guidelines.
Keywords:allergy and immunology, drug hypersensitivity, anesthesia, drug-related side effects and adverse reactions, anaphylaxis, epinephrine, Delphi technique, perioperative period, allergic reactions, hypersensitivity reaction, adrenaline, perioperative anaphylaxis, allergy testing, guideline
Publication status in journal:Published
Article version:Publisher's version of article
Place of publishing:Velika Britanija
Year of publishing:2019
Number of pages:str. e50-e64
Numbering:Vol. 123, iss. 1
PID:20.500.12556/DiRROS-12542 New window
ISSN on article:1471-6771
DOI:10.1016/j.bja.2019.04.044 New window
COBISS.SI-ID:2048510577 New window
Copyright:© 2019 British Journal of Anaesthesia
Note:Soavtor iz Slovenije: Peter Kopac; Nasl. z nasl. zaslona; Opis vira z dne 5. 6. 2019;
Publication date in DiRROS:09.10.2020
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Record is a part of a journal

Title:British journal of anaesthesia
Shortened title:Br. j. anaesth.
Publisher:Oxford University Press.
COBISS.SI-ID:515369241 New window


Description:Elsevier user licence
Licensing start date:24.05.2019

Secondary language

Keywords:alergija in imunologija, preobčutljivost za zdravila, anestezija, stranski in škodljivi učinki zdravil, anafilaksija, adrenalin, Delfska študija, perioperativno obdobje, alergijske reakcije, preobčutljivostna reakcija, epinefrin, perioperativna anafilaksija, alergijsko testiranje, smernica