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Title:Management of suspected immediate perioperative allergic reactions : an international overview and consensus recommendations
Authors:Garvey, Lene Heise (Author)
Dewachter, Pascale (Author)
Hepner, David L. (Author)
Mertes, Paul Michel (Author)
Voltolini, Susanna (Author)
Clarke, Russel C. (Author)
Cooke, Peter J. (Author)
Garcez, Tomaz (Author)
Guttormsen, Anne Berit (Author)
Ebo, Didier G. (Author)
Hopkins, Philip M. (Author)
Kopač, Peter (Author)
Tipology:1.02 - Review Article
Organisation:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Suspected perioperative allergic reactions are rare but can be life-threatening. The diagnosis is difficult to make in the perioperative setting, but prompt recognition and correct treatment is necessary to ensure a good outcome. A group of 26 international experts in perioperative allergy (anaesthesiologists, allergists, and immunologists) contributed to a modified Delphi consensus process, which covered areas such as differential diagnosis, management during and after anaphylaxis, allergy investigations, and plans for a subsequent anaesthetic. They were asked to rank the appropriateness of statements related to the immediate management of suspected perioperative allergic reactions. Statements were selected to represent areas where there is a lack of consensus in existing guidelines, such as dosing of epinephrine and fluids, the management of impending cardiac arrest, and reactions refractory to standard treatment. The results of the modified Delphi consensus process have been included in the recommendations on the management of suspected perioperative allergic reactions. This paper provides anaesthetists with an overview of relevant knowledge on the immediate and postoperative management of suspected perioperative allergic reactions based on current literature and expert opinion. In addition, it provides practical advice and recommendations in areas where consensus has been lacking in existing guidelines.
Keywords:allergy and immunology, drug hypersensitivity, anesthesia, drug-related side effects and adverse reactions, anaphylaxis, epinephrine, Delphi technique, perioperative period, allergic reactions, hypersensitivity reaction, adrenaline, perioperative anaphylaxis, allergy testing, guideline
Year of publishing:2019
Source:Velika Britanija
COBISS_ID:2048510577 Link is opened in a new window
ISSN on article:1471-6771
OceCobissID:515369241 Link is opened in a new window
DOI:10.1016/j.bja.2019.04.044 Link is opened in a new window
Note:Soavtor iz Slovenije: Peter Kopac; Nasl. z nasl. zaslona; Opis vira z dne 5. 6. 2019;
Files:URL URL - Source URL, visit
Journal:Br. j. anaesth.
Oxford University Press.
Rights:© 2019 British Journal of Anaesthesia
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Licensing start date:24.05.2019