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Title:Towards personalization of asthma treatment according to trigger factors
Authors:ID Niespodziana, Katarzyna (Author)
ID Borochova, Kristina (Author)
ID Pazderova, Petra (Author)
ID Schlederer, Thomas (Author)
ID Astafyeva, Natalia (Author)
ID Baranovskaya, Tatiana (Author)
ID Barbouche, Mohamed-Ridha (Author)
ID Beltiukov, Evgenyi (Author)
ID Berger, Angelika (Author)
ID Borzova, Elena (Author)
ID Bousquet, Jean (Author)
ID Zidarn, Mihaela, Klinika Golnik, Medicinska fakulteta UL (Author)
ID Valenta, Rudolf (Author)
Files:.pdf PDF - Presentation file, download (292,51 KB)
MD5: 7E21FD21CA8F771F802094489AE174FD
 
URL URL - Source URL, visit https://www.jacionline.org/article/S0091-6749(20)30193-7/pdf
 
Language:English
Typology:1.01 - Original Scientific Article
Organization:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract:Asthma is a severe and chronic disabling disease affecting more than 300 million people world-wide. While in the past few drugs for treatment of asthma were available, new treatment options are currently emerging which appear to be highly effective in certain subgroups of patients. Accordingly there is a need for biomarkers which allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on micro-arrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed which may discriminate two of the most common forms of asthma, i.e., allergen- and virus-triggered asthma. In this perspective we argue that classification of asthma patients according to these common trigger factors may open new possibilities for personalized management of asthma.
Keywords:allergy and immunology, asthma, signs and symptoms, respiratory, rhinovirus, allergens, microarray analysis, precision medicine, wheeze
Publication status:Published
Publication version:Version of Record
Place of publishing:ZDA
Publisher:Elsevier Inc.
Year of publishing:2020
Number of pages:str. 1529-1534
Numbering:Vol. 145, iss. 6
PID:20.500.12556/DiRROS-12302 New window
UDC:616-097
ISSN on article:1097-6825
DOI:10.1016/j.jaci.2020.02.001 New window
COBISS.SI-ID:2048639089 New window
Copyright:2020 The Authors
Note:Nasl. z nasl. zaslona; Soavtorica iz Slovenije: Mihaela Zidarn; Opis vira z dne 28. 2. 2020;
Publication date in DiRROS:31.07.2020
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Downloads:1082
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Record is a part of a journal

Title:The journal of allergy and clinical immunology
Shortened title:J. allergy clin. immunol.
Publisher:Elsevier
ISSN:1097-6825
COBISS.SI-ID:3614228 New window

Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:07.02.2020

Secondary language

Language:Undetermined
Keywords:alergija in imunologija, astma, respiratorni znaki in simptomi, rinovirus, alergeni, analiza mikromrež, personalizirana medicina, sopenje


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