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Title:Clinical significance of histologic subtyping of malignant pleural mesothelioma
Authors:ID Brčić, Luka (Author)
ID Kern, Izidor, Klinika Golnik (Author)
Files:.pdf PDF - Presentation file, download (1,86 MB)
MD5: 7FB5E9D004DA51FE3C51F4D3271B9B52
 
URL URL - Source URL, visit http://tlcr.amegroups.com/article/view/38662/pdf
 
Language:English
Typology:1.02 - Review Article
Organization:Logo UKPBAG - University Clinic of Respiratory and Allergic Diseases Golnik
Abstract: Malignant mesothelioma (MM) is uncommon, but very aggressive tumor arising from the mesothelial cells of pleura, pericardium, peritoneum, and tunica vaginalis. Despite multimodality treatments 5-year survival is only 5% after the diagnosis. Histology and TNM staging system are still the best prognostic factors. Furthermore, histologic subtype of MM determines the clinical management of the patients. According to the 2015 WHO classification, MM is divided into diffuse, localized and well differentiated papillary mesothelioma. Major histologic subtypes of diffuse MM, namely epithelioid, biphasic and sarcomatoid, have different prognosis. However, in the last decade it has become evident that more detailed subclassification and histologic/cytological characterization of MM have prognostic and perhaps predictive implications. In this review, major histologic subtypes and cytological features of MM are presented and their relation with prognosis and predictive biomarkers is discussed.
Keywords:malignant mesothelioma, epithelioid malignant mesothelioma, biphasic malignant mesothelioma, sarcomatoid malignant mesothelioma
Publication status:In print
Publication version:Author Accepted Manuscript
Place of publishing:Hong Kong
Publisher:AME Publishing Company
Year of publishing:2020
Number of pages:str.1-10
Numbering:Vol. 9, iss.
PID:20.500.12556/DiRROS-12161 New window
UDC:616-006
ISSN on article:2226-4477
DOI:10.21037/tlcr.2020.03.38 New window
COBISS.SI-ID:17124867 New window
Copyright:Translational lung cancer research
Note:Nasl. z nasl. zaslona; Opis vira z dne 27. 5. 2020;
Publication date in DiRROS:22.06.2020
Views:2887
Downloads:1497
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:
BRČIĆ, Luka and KERN, Izidor, 2020, Clinical significance of histologic subtyping of malignant pleural mesothelioma. Translational lung cancer research [online]. 2020. Vol. 9, p. 1–10. [Accessed 19 March 2025]. DOI 10.21037/tlcr.2020.03.38. Retrieved from: https://dirros.openscience.si/IzpisGradiva.php?lang=eng&id=12161
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Record is a part of a journal

Title:Translational lung cancer research
Shortened title:Transl. lung cancer res.
Publisher:Pioneer Bioscience
ISSN:2226-4477
COBISS.SI-ID:17120003 New window

Licences

License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Link:http://creativecommons.org/licenses/by-nc-nd/4.0/
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:22.06.2020

Secondary language

Language:Undetermined
Keywords:maligni mezoteliom, epiteloidni maligni mezoteliom, bifazni maligni mezoteliom, sarkomatoidni maligni mezoteliom


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