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112. Clinical significance of histologic subtyping of malignant pleural mesotheliomaLuka Brčić, Izidor Kern, 2020, review article Abstract: Malignant mesothelioma (MM) is uncommon, but very aggressive tumor arising from the mesothelial cells of pleura, pericardium, peritoneum, and tunica vaginalis. Despite multimodality treatments 5-year survival is only 5% after the diagnosis. Histology and TNM staging system are still the best prognostic factors. Furthermore, histologic subtype of MM determines the clinical management of the patients. According to the 2015 WHO classification, MM is divided into diffuse, localized and well differentiated papillary mesothelioma. Major histologic subtypes of diffuse MM, namely epithelioid, biphasic and sarcomatoid, have different prognosis. However, in the last decade it has become evident that more detailed subclassification and histologic/cytological characterization of MM have prognostic and perhaps predictive implications. In this review, major histologic subtypes and cytological features of MM are presented and their relation with prognosis and predictive biomarkers is discussed.
Keywords: malignant mesothelioma, epithelioid malignant mesothelioma, biphasic malignant mesothelioma, sarcomatoid malignant mesothelioma
Published in DiRROS: 22.06.2020; Views: 2245; Downloads: 1198
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113. Priporočila za obravnavo bolnikov s pljučnim rakomNina Boc, Martina Vrankar, Izidor Kern, Aleš Rozman, Karmen Stanič, Tomaž Štupnik, Mojca Unk, Maja Ebert Moltara, Vesna Zadnik, Katja Adamič, Jernej Benedik, Marko Bitenc, Jasna But-Hadžić, Anton Crnjac, Eva Ćirić, Tanja Čufer, Goran Gačevski, Marta Globočnik Kukovica, Kristina Gornik-Kramberger, Maja Ivanetič Pantar, Staša Jelerčič, Veronika Kloboves-Prevodnik, Mile Kovačević, Luka Ležaič, Mateja Marc-Malovrh, Katja Mohorčič, Bogdan Vidmar, Dušanka Vidovič, Gregor Vlačić, Ana Lina Vodušek, Rok Zbačnik, Ivana Žagar, 2019, professional monograph Published in DiRROS: 24.04.2020; Views: 2458; Downloads: 800
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114. Raba lesa v slovenskem biogospodarstvuDomen Arnič, Peter Prislan, Luka Juvančič, 2019, original scientific article Abstract: Krčenje zalog fosilnih goriv, netrajnostno izkoriščanje naravnih virov in podnebne spremembe so dejavniki, ki pospešujejo prehod v biogospodarstvo. Tovrsten prehod omogočajo tehnologije in novo znanje pretvorbe biomase v različne produkte, med seboj povezane v kaskadnih in (energetsko in snovno) krožnih proizvodnih ciklih. Eno ključnih področij biogospodarstva je področje rabe lesa, ki trenutno prispeva eno tretjino k skupni dodani vrednosti slovenskega biogospodarstva. Glede na stanje v državah s primerljivimi naravnimi in strukturnimi danostmi Slovenija v razvoju biogospodarstva zaostaja. V pričujočem delu smo predstavili generične dejavnike, ki vplivajo na razvoj biogospodarstva ter pripravili pregled stanja slovenskega biogospodarstva na področju rabe lesa. Stanje slovenskega biogospodarstva uvrščamo v širši evropski okvir ter ocenjujemo nadaljnje možnosti razvoja rabe lesa.
Keywords: biogospodarstvo, lesna biomasa, obnovljivi viri energije, raba lesa, biorafinerije, kaskadna raba lesa
Published in DiRROS: 20.12.2019; Views: 2631; Downloads: 758
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